Ki67\nm23基因在鼻咽癌中的表达及其意义(3)
 |
| 第1页 |
参见附件(2987KB，3页)。
总之，本研究表明在转移的鼻咽癌患者中，Ki67蛋白表达增高非常明显, 而nm23的表达降低非常明显，提示其癌组织的生物学行为较为凶险，预后较差，其二者的表达呈负相关，其间的关系尚未完全明了，值得我们从多技术、多角度进一步研究。
[参考文献]
[1]John WI, Lod S. Ki67 structure, function and new antibodies [J]. J Pathology,1992,168:161-162.
[2]申玉梅,齐文娟,申洪.鼻咽癌癌组织Ki67表达的阳性单位与癌转移TNM分期及患者生存时间的关系[J].中国体视学与图象分析,2010,15(2):213-218,161-162.
[3]王子彤,张海清,李世业,等.nm23-H1与CD44V6在非小细胞肺癌中的表达及意义[J].中国癌症杂志,2002,5(4):278-281.
[4]Zheng X, Hu L, Chen F, et al. Expression of Ki67 antigen, epidermal growth factor recept Epstein-Barrvirus-encodelate-ntmembrane protein (Lmp1)nasopharyngeal carcinoma [J]. Eur J Cancer B Oral Oncol,1994,3031(5):290-295.
[5]Cher L, Chew K, Rosenau W, et al. Cellular proliferation in prostatic adenocarcinoma asassessed by bromod-eoxyuridine up take and Ki67 and PCNA expression [J]. Prostate,1995,26:87.
[6]Hailat N, Keim DR, Melhem RF, et al. High levels of p19/nm23 protein in nuroblastoma are associated with N-mycgene amplification [J]. J Clin Invest,1991,88(1):341
[7]Roland NJ, Caslin AW, Bowie CL, et al. Has the cellular proliferation marker Ki67 any clinical relevance in squamous cell carcinoma of the head and neck [J]. Clin Otolaryngol,1994,19(1):13-18.
[8]Katakura H, Tanaka F, Oyanagi H, et al. Clinical significance of nm23 expression intersected pathologic stage Ⅰ, non-small cell lung cancer ......
您现在查看是摘要介绍页，详见PDF附件(2987KB，3页)。