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200例不育症患者血清性激素水平的含量分析(1)
http://www.100md.com 2011年12月5日 黄龙 麦静莹 刘志伟
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     [摘要] 目的:探讨不育症患者血清性激素水平与不育症的关系。方法:应用贝克曼DXI600全自动化学发光分析仪检测200例男性不育症患者血清性激素水平。结果:不育组患者的血清FSH和LH水平明显高于对照组(P<0.01);血清TT水平低于对照组(P<0.05)。无精或少精、精子活动力和活动不正常的不育症患者血清FSH和LH水平均明显高于对照组(P<0.01),血清TT水平低于对照组(P<0.05);液化时间不正常的不育症患者血清FSH、LH和TT水平与对照组比较,差异无统计学意义(P>0.05)。结论:对不育症患者血清性激素水平的检测意义重大,可以指导临床治疗。

    [关键词] 不育症;性激素水平;含量分析

    [中图分类号] R446.62 [文献标识码] B [文章编号] 1673-7210(2011)12(a)-093-02

    Content analysis of serum sex hormone levels of 200 patients with sterility

    HUANG Long, MAI Jingying, LIU Zhiwei

    Department of Clinical Laboratory, Xixiang People's Hospital of Bao'an District in Shenzhen City, Guangdong Province Shenzhen 518102, China

    [Abstract] Objective: To investigate the relationship between serum sex hormone levels and sterility in patients with sterility. Methods: The Beckman DXI600 automatic chemiluminescence analyzer was used to detect the serum sex hormone levels of 200 male patients with sterility. Results: The serum FSH and LH levels of the sterile group were significantly higher than those of the control group (P<0.01), and the serum TT level was lower than that of the control group (P<0.05). The serum FSH and LH levels of the sterile patients with aspermia, oligospermia and abnormal sperm activity and activity ratio were significantly higher than those of the control group (P<0.01), and the serum TT level was lower than that of the control group (P<0.05). The serum FSH, LH and TT levels of the sterile patients with abnormal liquefied time were not significantly different from those of the control group (P>0.05). Conclusion: There is of great significance to detect the sex hormone levels of patients with sterility, and it can guide the clinical treatment.

    [Key words] Sterility; Sex hormone levels; Content analysis

    精液常规分析只是测定精子的数量、活动力、活动率和形态,这些指标只能反映患者最基本的精液质量。有研究表明,任何引起生殖激素改变的因素都会影响男性的生育能力[1]。本文通过检测了不育症组及健康生育组的男性血清性激素LH、TT、FSH和PRL水平,探讨患者不育的原因,以指导不育症的临床治疗。现报道如下:

    1 资料与方法

    1.1 一般资料

    2009~2010年来我院不育门诊咨询就诊的200例男性患者,年龄23~41岁,平均32岁;不育年限2~15年。另选经过体检生殖系统正常且已经育有子女的成年健康男性50例作为对照组,年龄24~38岁,平均31岁。两组年龄比较差异无统计学意义(P>0 ......

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