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多囊卵巢综合征患者体重指数与脂蛋白代谢的相关性分析(1)
http://www.100md.com 2011年12月15日 张春华
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     [摘要] 目的:探讨多囊卵巢综合征(PCOS)患者不同的体重指数与脂质代谢的相关性。方法:收集门诊患者病历资料,按照PCOS诊断标准及体重指数(BMI)分为正常对照组30例、PCOS患者非肥胖组(non-fat group)39例与PCOS患者肥胖组(fat group)31例。三组分别检测空腹高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)及三酰甘油(TG)血清值。结果:HDL-C在3组的血清值分别为(1.53±0.23)、(1.47±0.41)、(1.22±0.20)mmol/L。经统计学分析对照组与PCOS非肥胖组血清比较,差异无统计学意义(P=0.572);PCOS肥胖组HDL-C值高于对照组及非肥胖组血清值(P=0.004、0.008);PCOS肥胖组与非肥胖组在LDL-C与TG血清值上比较,两组间差异均无统计学意义(P=0.637、0.588)。结论:HDL-C血清水平可能与PCOS的病情程度有相关性。

    [关键词] 多囊卵巢综合征;体重指数;高密度脂蛋白胆固醇;相关性

    [中图分类号] R711.75 [文献标识码] B [文章编号] 1673-7210(2011)12(b)-178-02

    Correlation analysis about lipoprotein serum level in different BMI patients of polycystic ovary syndrome

    ZHANG Chunhua

    Reproductive Health Center of Qianjiang District, Chongqing 409000, China

    [Abstract] Objective: To explore the correlation between polycystic ovarian syndrome (PCOS) patients′different body mass index and lipid metabolism of relevancy. Methods: Service medical records from outpatient were collected and divided into control group (30 cases), PCOS patients of non-fat group (39 cases) and PCOS patients of fat group (31 cases) in accordance with PCOS diagnostic criteria and body mass index (BMI). High-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C) and triglycerides (TG) serum values were tested in three groups in fasting plasma. Results: Serum levels of HDL-C in three groups were (1.53±0.23), (1.47±0.41), (1.22±0.20)mmol/L; by statistical analysis, there was no statistically significant difference between PCOS patients of non-fat group and control group (P=0.572); serum levels of HDL-C in PCOS patients of fat group were more that in the control group and PCOS patients of non-fat group (P=0.004, 0.008); serum levels of LDL-C and TG between PCOS patients of non-fat group and PCOS patients of fat group were no obvious difference (P=0.637, 0.588). Conclusion: The serum levels of HDL-C may be having a correlation with PCOS illness extent.

    [Key words] Polycystic ovary syndrome; Body mass index; High-density lipoprotein; Correlation ......

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