派瑞松联合外耳道冲洗治疗真菌性外耳道炎的临床研究(1)
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[摘要] 目的 探讨派瑞松联合外耳道冲洗治疗真菌性外耳道炎的方法及效果。 方法 随机选取本院2009年9月~2011年9月收治的80例真菌性外耳道炎患者分成两组，实验组42例，行派瑞松联合外耳道冲洗治疗；对照组38例，单纯行外耳道冲洗。随访10~15 d，比较两组患者治疗前后的病情积分、临床疗效和不良反应。 结果 随访期间两组内相比，治疗后患者的病情积分均低于治疗前(P <0.05)；两组间相比，实验组患者的病情积分、临床疗效和不良反应发生率均优于对照组(P <0.05)。 结论 应用派瑞松联合外耳道冲洗治疗真菌性外耳道炎，可显著减轻患者的病情恶化，避免不良反应，提高临床疗效。
[关键词] 派瑞松；外耳道冲洗；真菌性外耳道炎
[中图分类号] R764.1+1 [文献标识码] A [文章编号] 1673-7210(2012)02(c)-0040-02
Clinical study on Pevisone combined with canal irrigation in the treatment of fungal otitis externa
SUN Jun1 DU Youhong 2 LUO Tingjie1
1.Department of Otolaryngology, the People's Hospital of Lengshuijiang City, Hu'nan Province, Lengshuijiang 417500, China; 2. Department of Otolaryngology, the Center Hospital of Loudi City, Hu'nan Province, Loudi 417000, China
[Abstract] Objective To evaluate the methods and results of Pevisone combined with canal irrigation in the treatment of fungal otitis externa. Methods 80 cases which were selected from September 2009 to September 2011 admitted to hospital with fungal otitis externa were randomly divided into two groups, experimental group of 42 patients was given canal irrigation combined with Pevisone; control group of 38 cases was given canal irrigation. Follow-up of 10-15 days, two groups were compared before and after treatment of the disease points, clinical efficacy and adverse reactions. Results During follow-up comparing in two groups after treatment, the patient's condition points were lower than before treatment (P <0.05); the disease points, clinical efficacy and adverse reaction rates of experimental group were better than the control group (P <0.05). Conclusion Canal irrigation combined with Pevisone in the treatment of fungal otitis externa, can significantly reduce the patient's condition deteriorated, avoid adverse reactions, improve clinical efficacy.
[Key words] Pevisone; Canal irrigation; Fungal otitis externa
真菌性外耳道炎目前在耳鼻喉科门诊较为常见，是由于霉菌感染所形成的外耳道皮肤和皮下组织弥漫性炎症。临床治疗过去多采用单纯的外耳道冲洗，但疗效欠佳，严重者甚至可影响患者听力及生活质量。因此，为探讨药物[曲安奈德益康唑乳膏(商品名：派瑞松)]联合外耳道冲洗治疗真菌性外耳道炎的方法及效果，给临床治疗提供参考 ......
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