QRS时限与慢性心力衰竭患者预后的相关性分析(1)
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[摘要] 目的 探讨QRS时限在慢性心力衰竭患者预后中的表达及两者之间的相关性。 方法 回顾性分析我院2008年10月~2010年1月收治的75例慢性心力衰竭患者，对其心电图资料进行分析，根据QRS值分为<120 ms 组和≥120 ms 组，比较两组的左心室射血分数(LVEF)值及两组患者治疗后1年内患者预后情况，包括出现急性心力衰竭或死亡病例。 结果 两组一般资料比较，在冠心病及扩张型心肌病两方面比较，差异有统计学意义(P < 0.05)。在其他并发病及临床ACEI及β受体阻滞剂类药物应用方面比较，差异无统计学意义(P > 0.05)。两组LVEF比较，<120 ms组显著高于≥120ms组(P < 0.05)。QRS<120 ms组1年内终点事件发生率为11.1%，QRS≥120 ms组1年内终点事件发生率为35.9%，两者比较差异有统计学意义(P < 0.05)。 结论 QRS时限≥120 ms 的患者LVEF降低，且心血管终点事件发生率上升，因此临床上慢性心力衰竭患者QRS时限延长对其预后有一定的相关性。
[关键词] QRS 时限；慢性心力衰竭；预后
[中图分类号] R541.6 [文献标识码] A [文章编号] 1673-7210(2012)04(a)-0081-02
Relation dependability limit with the prognosis chronic heart failure of QRS duration
YANG Lanying1 WANG Lanfang2
1.Yan'an University Hospital, Shaanxi Province, Yan′an 716000, China; 2.The First Hospital of Yulin City, Shaanxi Province, Suide 718000, China
[Abstract] Objective To evaluate the relation dependability of QRS and the prognosis CFH. Methods 75 cases were retrospectively analyzed who had CFH treated from October 2008 to January 2010. According to the level of QRS, the 75 cases were randomly divided into 2 groups of < 120 ms group and ≥120 ms group. The left ventricular ejection fraction (LVEF), endpoint events and the rate of recurrent acute heart failure or deaths within 1 year were contrasted. Results The general of data were significant differences in the level of coronary heart disease and dilated cardiomyopathy (P < 0.05). The others cause and ACEI and β receptor blocking pharmacon were no significant differences (P > 0.05). LVEF of the CHF in QRS ≥120 ms group was significantly lower than QRS<120 ms group, endpoint events was 35.9% in the ≥120 ms group, was significantly higher than QRS<120 ms group (11.1%)(P < 0.05). Conclusion The groups of ≥120 ms of QRS has higher LVEF, the rate of endpoint events is higher, prolonged duration of QRS might have the predictive value on prognosis in CHF.
[Key words] QRS duration; Chronic heart failure; Prognosis
近年慢性心力衰竭(chronic heart failue，CHF)发病率有上升的趋势，具有较高患病率和病死率[1]。随着医疗技术的发展与CHF治疗模式的转变，CHF的预防和治疗已成为临床的热点问题，而QRS时限目前广泛应用于临床CHF的预防中 ......
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