老年与中青年甲状腺切除手术临床对比分析(1)
[摘要] 目的 探讨老年与中青年甲状腺切除手术的临床疗效和安全性。 方法 行甲状腺切除术患者182例按年龄分为老年组(32例)和中青年组(150例)，观察两组手术时间、术中出血量、术后住院时间及随访并发症发生率和复发率。 结果 老年组手术时间和术后住院时间明显多于中青年组(P < 0.05)，而术中出血量两组比较差异无统计学意义(P > 0.05)；两组暂时性、永久性并发症各指标比较差异均无统计学意义(均P > 0.05)；老年组并发症发生率、复发率分别为15.63%(5/32)、6.25%(2/32)，中青年组为11.33%(17/150)、3.33%(5/150)，差异无统计学意义(P > 0.05)。 结论 老年患者甲状腺切除手术安全可行，应在严格掌握适应证情况下积极手术治疗。
[关键词] 老年；甲状腺切除；手术
[中图分类号] R653 [文献标识码] A [文章编号] 1673-7210(2012)07(a)-0070-02
, 百拇医药
Clinical comparative analysis of thyroidectomy between elderly and young patients
CAI Jianpu
Department of the First General Surgery, the People's Hospital of Ru'nan County, He'nan Province, Ru'nan 463300, China
[Abstract] Objective To investigate the clinical efficacy and safety of thyroidectomy between elderly and young patients. Methods 182 cases of patients underwent thyroidectomy were divided into the elderly group (32 cases) and the young group (150 cases) according to age. The operative time, amount of bleeding in operation, postoperative hospitalization time and incidence of complications and recurrence rate were observed. Results The operative time and postoperative hospitalization time of the elderly group were significant longer than those of the young group (P < 0.05); there was no significant difference in intraoperative blood loss between the two groups (P > 0.05). There was no significant difference in temporary and permanent complications index between the two groups (P > 0.05). The incidence of complications and recurrence rate of the elderly group were 15.63% (5/32) and 6.25% (2/32) respectively, which were 11.33% (17/150) and 3.33% (5/150) in the young group, there were no statistically significance differences (P < 0.05). Conclusion Thyroidectomy application in elderly patients is feasible and safe. Elderly patients should give positive surgical treatment under strict control of indications.
, 百拇医药
[Key words] Elderly; Thyroidectomy; Surgery
甲状腺疾病是普外科的常见疾病，病种多，症状隐匿，若不给予及时有效治疗，会造成机体内分泌功能严重失调，对心血管系统及肝肾功能造成很大损害，带来诸多并发症甚至危及生命[1]。药物治疗疗程长，不易根除，复发率高[2]，故临床主要采用外科手术切除。老年患者各项生理机能呈退行性改变，加之多伴有心脑血管疾病，应激代偿能力减弱，麻醉和手术耐受性较差，极易发生严重呼吸和循环改变，导致心血管意外。因此，很多医生担心手术风险而选择药物治疗，给老年患者带来长期的疾病折磨。为此，笔者观察老年与中青年甲状腺切除手术的临床疗效和安全性，以期为临床应用提供参考。
1 资料与方法
1.1 一般资料
选择2009年6月～2011年6月于我科行甲状腺切除手术患者182例，按年龄分为老年组和中青年组。老年组32例，男8例，女24例；年龄65～80岁，平均(69.1±4.2)岁；甲状腺腺瘤9例，结节性甲状腺肿20例，甲状腺癌3例。中青年组150例，男35例，女115例；年龄20～64岁，平均(47.1±5.8)岁；甲状腺腺瘤52例，结节性甲状腺肿86例，甲状腺癌12例。所有患者均无严重心、肝、肺、肾功能不全，排除妊娠期和哺乳期妇女，经医院伦理委员会批准，患者签署知情同意书。两组一般情况比较，差异无统计学意义(P > 0.05)，具有可比性。, 百拇医药(蔡建圃)
[关键词] 老年；甲状腺切除；手术
[中图分类号] R653 [文献标识码] A [文章编号] 1673-7210(2012)07(a)-0070-02
, 百拇医药
Clinical comparative analysis of thyroidectomy between elderly and young patients
CAI Jianpu
Department of the First General Surgery, the People's Hospital of Ru'nan County, He'nan Province, Ru'nan 463300, China
[Abstract] Objective To investigate the clinical efficacy and safety of thyroidectomy between elderly and young patients. Methods 182 cases of patients underwent thyroidectomy were divided into the elderly group (32 cases) and the young group (150 cases) according to age. The operative time, amount of bleeding in operation, postoperative hospitalization time and incidence of complications and recurrence rate were observed. Results The operative time and postoperative hospitalization time of the elderly group were significant longer than those of the young group (P < 0.05); there was no significant difference in intraoperative blood loss between the two groups (P > 0.05). There was no significant difference in temporary and permanent complications index between the two groups (P > 0.05). The incidence of complications and recurrence rate of the elderly group were 15.63% (5/32) and 6.25% (2/32) respectively, which were 11.33% (17/150) and 3.33% (5/150) in the young group, there were no statistically significance differences (P < 0.05). Conclusion Thyroidectomy application in elderly patients is feasible and safe. Elderly patients should give positive surgical treatment under strict control of indications.
, 百拇医药
[Key words] Elderly; Thyroidectomy; Surgery
甲状腺疾病是普外科的常见疾病，病种多，症状隐匿，若不给予及时有效治疗，会造成机体内分泌功能严重失调，对心血管系统及肝肾功能造成很大损害，带来诸多并发症甚至危及生命[1]。药物治疗疗程长，不易根除，复发率高[2]，故临床主要采用外科手术切除。老年患者各项生理机能呈退行性改变，加之多伴有心脑血管疾病，应激代偿能力减弱，麻醉和手术耐受性较差，极易发生严重呼吸和循环改变，导致心血管意外。因此，很多医生担心手术风险而选择药物治疗，给老年患者带来长期的疾病折磨。为此，笔者观察老年与中青年甲状腺切除手术的临床疗效和安全性，以期为临床应用提供参考。
1 资料与方法
1.1 一般资料
选择2009年6月～2011年6月于我科行甲状腺切除手术患者182例，按年龄分为老年组和中青年组。老年组32例，男8例，女24例；年龄65～80岁，平均(69.1±4.2)岁；甲状腺腺瘤9例，结节性甲状腺肿20例，甲状腺癌3例。中青年组150例，男35例，女115例；年龄20～64岁，平均(47.1±5.8)岁；甲状腺腺瘤52例，结节性甲状腺肿86例，甲状腺癌12例。所有患者均无严重心、肝、肺、肾功能不全，排除妊娠期和哺乳期妇女，经医院伦理委员会批准，患者签署知情同意书。两组一般情况比较，差异无统计学意义(P > 0.05)，具有可比性。, 百拇医药(蔡建圃)