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2004~2010年鲍曼不动杆菌医院感染及耐药性变化(1)
http://www.100md.com 2012年8月25日 张亚彬 兰小鹏
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     [摘要] 目的 研究2004~2010年鲍曼不动杆菌医院感染的分布特点及耐药性变化趋势。 方法 收集2004~2010年我院住院患者标本中分离的鲍曼不动杆菌及其耐药率资料。采用最小抑菌浓度(MIC)法,比较鲍曼不动杆菌对常见14种抗生素的耐药性,分析7年来鲍曼不动杆菌的耐药性变化趋势。 结果 7年间共分离到鲍曼不动杆菌1 518株,数量和所占总分离菌数的比例均呈逐年递增趋势。标本类型主要以呼吸道标本为主,其中,痰、肺泡灌洗液、咽拭子分别占分离标本的前三位。鲍曼不动杆菌对目前临床上大部分抗生素有较高耐药率,且呈现逐年上升趋势。 结论 临床医生需要重视微生物培养,及时参考细菌药敏结果合理用药,同时医务人员需关注手部清洁和消毒,避免耐药菌株的产生和播散。

    [关键词] 鲍曼不动杆菌;医院感染;耐药性;多重耐药菌

    [中图分类号] R378 [文献标识码] A [文章编号] 1673-7210(2012)08(c)-0097-03

    Nosocomial infection and drug resistance changes of acinetobacter baumannii from 2004 to 2010

    ZHANG Yabin LAN Xiaopeng*

    Department of Clinical Laboratory, Fuzhou General Hospital of Nanjing Military Region, Fujian Province, Fuzhou 350025, China

    [Abstract] Objective To study the distribution characteristics of nosocomial infection and drug resistance changes of acinetobacter baumannii from 2004 to 2010. Methods Data of acinetobacter baumannii separated from specimens of inpatients in our hospital from 2004 to 2010 and its drug resistance rate were selected. The drug resistance of acinetobacter baumannii to 14 kinds of common antibiotics was compared by the minimum inhibitory concentration (MIC) method and the change trend of drug resistance of acinetobacter baumannii in the recent 7 years was analyzed. Results A total of 1 518 strains of acinetobacter baumannii were separated during 7 years and the number and proportion showed an increasing trend. The main types of specimens were respiratory specimens, of which sputum, bronchoalveolar lavage fluid and throat swab accounted for the top three of all specimens ......

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