中药外敷辅助妇科术后胃肠功能恢复的临床效果和与血清炎性因子的关联(1)
摘要 目的：分析中藥外敷对妇科腹部手术创伤后胃肠功能障碍的干预效果，同时分析其控制炎性反应的效果。方法：选择2014年2月至2014年6月在夷陵医院治疗的符合纳入标准的妇科手术患者90例，随机分为2组。观察组在常规治疗的基础上，采用中药包外敷，并加用红外线照射提高中药吸收效果；对照组采用常规治疗。观察比较患者在术后首次排气、排便时间情况；术前、术后第1天、第4天血清胃动素、炎性反应因子白介素-6(IL-6)、C-反应蛋白(CRP)的变化情况。结果：中药外敷组患者术后排气排便时间均早于对照组；患者术后第1天胃肠激素胃动素(MOT)水平较术前均明显降低，术后第4天MOT水平较术后第1天均明显升高，且中药外敷组MOT水平高于对照组；两患者术后第1天IL-6、CRP水平较术前均明显增高，术后晨IL-6、CRP水平较术后第1天均回落，且中药观察组术水平优于对照组。结论：中药包外敷可使腹部术后患者肛门排气排便时间提前，促进胃肠功能早期恢复，且有控制炎性反应进展的功效。
关键词 外敷；胃肠功能障碍；白介素-6；胃动素；C-反应蛋白
, 百拇医药
Abstract Objective：To analyze the intervention effects of external application of Chinese herbs to gastrointestinal dysfunction after gynecological surgery in abdomen and its effects on controlling inflammatory response. Methods：A total of 90 patients met the inclusion criteria with gynecological surgery who were treated in Yiling Hospital from February 2014 to June 2014 were enrolled in this study and they were randomized into two groups. In therapeutic group， based on conventional treatment， external application of Chinese herbs bags was adopted. Infrared radiation was also used to improve the absorption effect. In control group conventional treatment was adopted. The patients′ first time of postoperative exhaust and defecation and the changes of serum motilin， inflammatory factor interleukin-6 (IL-6) and acute phase protein C-reactive protein (CRP) before the surgery， on 1 d and 4 d day after the surgery were observe and compared. Results：The exhaust and defecation time of patients in the therapeutic group were earlier than those in the control group. Gastrointestinal hormone motilin (MOT) on 1 d morning after the surgery was significantly reduced in both groups compared with the preoperative content. Gastrointestinal hormone motilin (MOT) on 4 d morning after surgery were significantly increased compared with 1 d and the content in the therapeutic group was higher than in the control group； The levels of IL-6 and CRP on the first day morning after operation were significantly higher than those before the operation. The levels of IL-6 and CRP on the fourth day morning after operation fell which were lower than those on 1 d. And the treatment in the group with Chinese herbs was much better than in the control group. Conclusion：Treating patients after abdominal surgery with external application of Chinese herbs bags could bring the time of anal exhaust and defecation earlier. It could also improve the recovery of gastrointestinal function and control the progression of inflammation., 百拇医药(何世梅 黄玉蓉 易蓉 李伟 高志红 柳长柏)
关键词 外敷；胃肠功能障碍；白介素-6；胃动素；C-反应蛋白
, 百拇医药
Abstract Objective：To analyze the intervention effects of external application of Chinese herbs to gastrointestinal dysfunction after gynecological surgery in abdomen and its effects on controlling inflammatory response. Methods：A total of 90 patients met the inclusion criteria with gynecological surgery who were treated in Yiling Hospital from February 2014 to June 2014 were enrolled in this study and they were randomized into two groups. In therapeutic group， based on conventional treatment， external application of Chinese herbs bags was adopted. Infrared radiation was also used to improve the absorption effect. In control group conventional treatment was adopted. The patients′ first time of postoperative exhaust and defecation and the changes of serum motilin， inflammatory factor interleukin-6 (IL-6) and acute phase protein C-reactive protein (CRP) before the surgery， on 1 d and 4 d day after the surgery were observe and compared. Results：The exhaust and defecation time of patients in the therapeutic group were earlier than those in the control group. Gastrointestinal hormone motilin (MOT) on 1 d morning after the surgery was significantly reduced in both groups compared with the preoperative content. Gastrointestinal hormone motilin (MOT) on 4 d morning after surgery were significantly increased compared with 1 d and the content in the therapeutic group was higher than in the control group； The levels of IL-6 and CRP on the first day morning after operation were significantly higher than those before the operation. The levels of IL-6 and CRP on the fourth day morning after operation fell which were lower than those on 1 d. And the treatment in the group with Chinese herbs was much better than in the control group. Conclusion：Treating patients after abdominal surgery with external application of Chinese herbs bags could bring the time of anal exhaust and defecation earlier. It could also improve the recovery of gastrointestinal function and control the progression of inflammation., 百拇医药(何世梅 黄玉蓉 易蓉 李伟 高志红 柳长柏)