摘要 骨质疏松症(Osteoporosis，OP)是一种以骨量低下、骨微结构破坏，导致脆性骨折的退行性骨病。阿尔茨海默病(Alzheimer′s Disease，AD)主要表现为记忆力减退和认知功能障碍。表面上看OP和AD不论是在症状还是在体征方面都截然不同，但越来越多的研究表明两者存在一些共有的致病因素、发病机制和信号通路。

    关键词 骨质疏松；阿尔茨海默病；骨密度；淀粉样蛋白

    Abstract Osteoporosis (OP) can be defined as a degenerative bone disease characterized by low bone mass and the microarchitectural deterioration， with a consequent increase in the fragility of bone and susceptibility to fracture. Alzheimer′s disease (AD) is a disease with memory loss and cognitive impairment. Despite their different signs and symptoms ......