姜黄素对大鼠视网膜缺血/再灌注损伤时内质网应激的影响(5)
综上所述，姜黄素可减轻大鼠RIRI，其机制可能与抑制ERS介导的细胞凋亡有关。
参考文献
[1]Fan Z，Yao J，Li Y，et al.Anti-inflammatory and antioxidant effects of curcumin on acute lung injury in a rodent model of intestinal ischemia reperfusion by inhibiting the pathway of NF-Kb[J].Int J Clin Exp Pathol，2015，8(4)：3451-3459.
[2]Zhang HJ，Xing YQ，Jin W，et al.Effects of curcumin on interleukin-23 and interleukin-17 expression in rat retina after retinal ischemia-reperfusion injury[J].Int J Clin Exp Pathol，2015，8(8)：9223-9231.
, 百拇医药
[3]Wang S，Ye Q，Tu J，et al.Curcumin protects against hypertension aggravated retinal ischemia/reperfusion in a rat strokemodel[J].Clin Exp Hypertens，2017，39(8)：711-717.
[4]Chen YJ，Huang YS，Chen JT，et al.Protective effects of glucosamine on oxidative-stress and ischemia/reperfusion-induced retinal injury[J].Invest Ophthalmol Vis Sci，2015，56(3)：1506-1516.
[5]王賽斌，姬斌，黄晓燕，等.姜黄素对自发性高血压大鼠缺血再灌注后视网膜细胞凋亡及p53表达的影响[J].浙江中医药大学学报，2012，36(7)：798-802.
, 百拇医药
[6]Hu T，You Q，Chen D，et al.Inhibiting Matrix Metalloproteinase 3 Ameliorates Neuronal Loss in the Ganglion Cell Layer of Rats in Retinal Ischemia/Reperfusion[J].Neurochem Res，2016，41(5)：1107-1118.
[7]Xu YP，Han F，Tan J.Edaravone protects the retina against ischemia/reperfusioninduced oxidative injury through the PI3K/Akt/Nrf2 pathway[J].Mol Med Rep，2017，16(6)：9210-9216.
[8]Seong H，Ryu J，Yoo WS，et al.Resveratrol Ameliorates Retinal Ischemia/Reperfusion Injury in C57BL/6J Mice viaDownregulation of Caspase-3[J].Curr Eye Res，2017，42(12)：1650-1658.
, http://www.100md.com
[9]Bomsztyk K，Mar D，An D，et al.Experimental acute lung injury induces multi-organ epigenetic modifications in key angiogenic genes implicated in sepsis-associated endothelial dysfunction[J].Crit Care，2015，19(1)：225.
[10]Yin J，Tu C，Zhao J，et al.Exogenous hydrogen sulfide protects against global cerebral ischemia/reperfusion injury via its anti-oxidative，anti-inflammatory and anti-apoptotic effects in rats[J].Brain Res，2013，1491：188-196.
, 百拇医药
[11]Cheng P，Wang F，Chen K，et al.Hydrogen sulfide ameliorates ischemia/reperfusion-induced hepatitis by inhibiting apoptosis and autophagy pathways[J].Mediators Inflamm，2014，2014：935251.
[12]Kawamura T，Wakabayashi N，Shigemura N，et al.Hydrogen gas reduces hyperoxic lung injury via the Nrf2 pathway in vivo[J].Am J Physiol Lung Cell Mol Physiol，2013，304(10)：L646-L656.
[13]Meng G，Wang J，Xiao Y，et al.GYY4137 protects against myocardial ischemia and reperfusion injury by attenuating oxidative stress and apoptosis in rats[J].J Biomed Res，2015，29(3)：203-213., 百拇医药(彭栋梁 王晓娜 杨军)
参考文献
[1]Fan Z，Yao J，Li Y，et al.Anti-inflammatory and antioxidant effects of curcumin on acute lung injury in a rodent model of intestinal ischemia reperfusion by inhibiting the pathway of NF-Kb[J].Int J Clin Exp Pathol，2015，8(4)：3451-3459.
[2]Zhang HJ，Xing YQ，Jin W，et al.Effects of curcumin on interleukin-23 and interleukin-17 expression in rat retina after retinal ischemia-reperfusion injury[J].Int J Clin Exp Pathol，2015，8(8)：9223-9231.
, 百拇医药
[3]Wang S，Ye Q，Tu J，et al.Curcumin protects against hypertension aggravated retinal ischemia/reperfusion in a rat strokemodel[J].Clin Exp Hypertens，2017，39(8)：711-717.
[4]Chen YJ，Huang YS，Chen JT，et al.Protective effects of glucosamine on oxidative-stress and ischemia/reperfusion-induced retinal injury[J].Invest Ophthalmol Vis Sci，2015，56(3)：1506-1516.
[5]王賽斌，姬斌，黄晓燕，等.姜黄素对自发性高血压大鼠缺血再灌注后视网膜细胞凋亡及p53表达的影响[J].浙江中医药大学学报，2012，36(7)：798-802.
, 百拇医药
[6]Hu T，You Q，Chen D，et al.Inhibiting Matrix Metalloproteinase 3 Ameliorates Neuronal Loss in the Ganglion Cell Layer of Rats in Retinal Ischemia/Reperfusion[J].Neurochem Res，2016，41(5)：1107-1118.
[7]Xu YP，Han F，Tan J.Edaravone protects the retina against ischemia/reperfusioninduced oxidative injury through the PI3K/Akt/Nrf2 pathway[J].Mol Med Rep，2017，16(6)：9210-9216.
[8]Seong H，Ryu J，Yoo WS，et al.Resveratrol Ameliorates Retinal Ischemia/Reperfusion Injury in C57BL/6J Mice viaDownregulation of Caspase-3[J].Curr Eye Res，2017，42(12)：1650-1658.
, http://www.100md.com
[9]Bomsztyk K，Mar D，An D，et al.Experimental acute lung injury induces multi-organ epigenetic modifications in key angiogenic genes implicated in sepsis-associated endothelial dysfunction[J].Crit Care，2015，19(1)：225.
[10]Yin J，Tu C，Zhao J，et al.Exogenous hydrogen sulfide protects against global cerebral ischemia/reperfusion injury via its anti-oxidative，anti-inflammatory and anti-apoptotic effects in rats[J].Brain Res，2013，1491：188-196.
, 百拇医药
[11]Cheng P，Wang F，Chen K，et al.Hydrogen sulfide ameliorates ischemia/reperfusion-induced hepatitis by inhibiting apoptosis and autophagy pathways[J].Mediators Inflamm，2014，2014：935251.
[12]Kawamura T，Wakabayashi N，Shigemura N，et al.Hydrogen gas reduces hyperoxic lung injury via the Nrf2 pathway in vivo[J].Am J Physiol Lung Cell Mol Physiol，2013，304(10)：L646-L656.
[13]Meng G，Wang J，Xiao Y，et al.GYY4137 protects against myocardial ischemia and reperfusion injury by attenuating oxidative stress and apoptosis in rats[J].J Biomed Res，2015，29(3)：203-213., 百拇医药(彭栋梁 王晓娜 杨军)