淫羊藿化学成分的分离与鉴定(4)
4讨论
在淫羊藿叶样品中通过分离得到了7个化合物,分别为:5,7,4′三甲氧基4苯基香豆素;2,3,4,6,7五甲氧基菲;3,5,7,4′四甲氧基黄酮;4,5,-二羟基2,3,6三甲氧基9,10二氢菲;4羟基肉桂酸甲酯;4羟基(2E)-2壬烯酸;4羟基3异戊二烯基苯甲酸(7)[19]。化合物17为首次从淫羊藿属分离得到化合物。
参考文献
[1]国家药典委员会.中华人民共和国药典[S].北京:中国医药科技出版社,2015:21.
[2]孟宁,孔凯,李师翁,等.淫羊藿属植物化学成分及药理活性研究进展[J].西北植物学报,2010,30(5):10631073.
[3]谢娟平,孙文基.淫羊藿属植物化学成分及药理研究进展[J].海峡药学,2006,18(5):1720.
, 百拇医药
[4]宋剑,王超,李知遥,等.淫羊藿总黄酮抗老年痴呆化学成分研究[J].中国现代中药,2009,11(8):2326.
[5]李牡丹,石旭,关萍.淫羊藿的研究进展[J].山地农业生物学报,2009,28(2):170174.
[6]韩广轩,王麦莉,张军东,等.淫羊藿化学成分的研究进展[J].药学实践杂志,2002,20(6):359361.
[7]韩冰,沈彤,鞠建华,等.淫羊藿属植物化学成分研究概况[J].国外医药:植物药分册,2003,18(4):151153.
[8]袁航,曹树萍,陈抒云,等.淫羊藿的化学成分及质量控制研究进展[J].中草药,2014,45(24):36303640.
[9]郭丽娜,马莹慧,赵伟,等.淫羊藿属植物中化学成分分析研究进展[J].中国新药杂志,2013,22(8):919922,936.
, http://www.100md.com
[10]李遇伯,孟繁浩,鹿秀梅,等.淫羊藿化学成分的研究[J].中国中药杂志,2005,30(8):586588.
[11]刘丽萍,徐晓芳,孙东东,等.淫羊藿水提部位化学成分的HPLCESIQTOFMS分析[J].中国实验方剂学杂志,2014,20(19):112116.
[12]Leong YW,Kang CC,Harrison LJ,et al.Phenanthrenes,dihydrophenanthrenes and bibenzyls from the orchid bulbophyllum vaginatum[J].Phytochemistry,1997,44(1):157165.
[13]Radwan MM,Elsohly MA,Slade D,et al.Noncannabinoid constituents from a high potency Cannabis sativa variety[J].Phytochemistry,2008,69(14):26272633.
, http://www.100md.com
[14]Ito A,Chai HB,Shin YG,et al.Cytotoxic constituents of the roots of exostema acuminatum[J].Tetrahedron,2000,56(10):64016405.
[15]Sutthanut K,Sripanidkulchai B,Yenjai C,et al.Simultaneous identification and quantitation of 11 flavonoid constituents in Kaempferia parviflora by gas chromatography[J].J Chromatogr A,2007,1143(12):227233.
[16]Hayashi K,Komura S,Isaji N,et al.Isolation of antioxidative compounds from brazilian propolis:3,4dihydroxy5prenylcinnamic acid,a novel potent antioxidant[J].Chem Pharm Bull,1999,47(11):15211524.
, http://www.100md.com
[17]Percec V,Peterca M,Sienkowska MJ,et al.Synthesis and retrostructural analysis of libraries of AB3 and constitutional isomeric AB2 phenylpropyl etherbased supramolecular dendrimers[J].J Am Chem Soc,2006,128(10):33243334.
[18]McGrath CE,Tallman KA,Porter NA,et al.Structureactivity analysis of diffusible lipid electrophiles associated with phospholipid peroxidation:4hydroxynonenal and 4oxononenal analogues[J].Chem Res Toxicol,2011,24(3):357370.
[19]冯晶.淫羊藿的研究进展[J].中药研究,2012,34(9):7475.
(2017-05-17收稿責任编辑:杨觉雄), http://www.100md.com(黄楚燕 梁宏宇)
在淫羊藿叶样品中通过分离得到了7个化合物,分别为:5,7,4′三甲氧基4苯基香豆素;2,3,4,6,7五甲氧基菲;3,5,7,4′四甲氧基黄酮;4,5,-二羟基2,3,6三甲氧基9,10二氢菲;4羟基肉桂酸甲酯;4羟基(2E)-2壬烯酸;4羟基3异戊二烯基苯甲酸(7)[19]。化合物17为首次从淫羊藿属分离得到化合物。
参考文献
[1]国家药典委员会.中华人民共和国药典[S].北京:中国医药科技出版社,2015:21.
[2]孟宁,孔凯,李师翁,等.淫羊藿属植物化学成分及药理活性研究进展[J].西北植物学报,2010,30(5):10631073.
[3]谢娟平,孙文基.淫羊藿属植物化学成分及药理研究进展[J].海峡药学,2006,18(5):1720.
, 百拇医药
[4]宋剑,王超,李知遥,等.淫羊藿总黄酮抗老年痴呆化学成分研究[J].中国现代中药,2009,11(8):2326.
[5]李牡丹,石旭,关萍.淫羊藿的研究进展[J].山地农业生物学报,2009,28(2):170174.
[6]韩广轩,王麦莉,张军东,等.淫羊藿化学成分的研究进展[J].药学实践杂志,2002,20(6):359361.
[7]韩冰,沈彤,鞠建华,等.淫羊藿属植物化学成分研究概况[J].国外医药:植物药分册,2003,18(4):151153.
[8]袁航,曹树萍,陈抒云,等.淫羊藿的化学成分及质量控制研究进展[J].中草药,2014,45(24):36303640.
[9]郭丽娜,马莹慧,赵伟,等.淫羊藿属植物中化学成分分析研究进展[J].中国新药杂志,2013,22(8):919922,936.
, http://www.100md.com
[10]李遇伯,孟繁浩,鹿秀梅,等.淫羊藿化学成分的研究[J].中国中药杂志,2005,30(8):586588.
[11]刘丽萍,徐晓芳,孙东东,等.淫羊藿水提部位化学成分的HPLCESIQTOFMS分析[J].中国实验方剂学杂志,2014,20(19):112116.
[12]Leong YW,Kang CC,Harrison LJ,et al.Phenanthrenes,dihydrophenanthrenes and bibenzyls from the orchid bulbophyllum vaginatum[J].Phytochemistry,1997,44(1):157165.
[13]Radwan MM,Elsohly MA,Slade D,et al.Noncannabinoid constituents from a high potency Cannabis sativa variety[J].Phytochemistry,2008,69(14):26272633.
, http://www.100md.com
[14]Ito A,Chai HB,Shin YG,et al.Cytotoxic constituents of the roots of exostema acuminatum[J].Tetrahedron,2000,56(10):64016405.
[15]Sutthanut K,Sripanidkulchai B,Yenjai C,et al.Simultaneous identification and quantitation of 11 flavonoid constituents in Kaempferia parviflora by gas chromatography[J].J Chromatogr A,2007,1143(12):227233.
[16]Hayashi K,Komura S,Isaji N,et al.Isolation of antioxidative compounds from brazilian propolis:3,4dihydroxy5prenylcinnamic acid,a novel potent antioxidant[J].Chem Pharm Bull,1999,47(11):15211524.
, http://www.100md.com
[17]Percec V,Peterca M,Sienkowska MJ,et al.Synthesis and retrostructural analysis of libraries of AB3 and constitutional isomeric AB2 phenylpropyl etherbased supramolecular dendrimers[J].J Am Chem Soc,2006,128(10):33243334.
[18]McGrath CE,Tallman KA,Porter NA,et al.Structureactivity analysis of diffusible lipid electrophiles associated with phospholipid peroxidation:4hydroxynonenal and 4oxononenal analogues[J].Chem Res Toxicol,2011,24(3):357370.
[19]冯晶.淫羊藿的研究进展[J].中药研究,2012,34(9):7475.
(2017-05-17收稿責任编辑:杨觉雄), http://www.100md.com(黄楚燕 梁宏宇)