【摘要】 目的 探讨快速检测D-二聚体(DD)在肺栓塞诊断中的临床意义。方法 使用全自动免疫分析系统VIDAS DD测定法对可疑静脉血栓患者血浆中纤维蛋白降解产物D-二聚体进行检测，并对这些可疑肺栓塞患者进行1年随访，了解是否有肺栓塞症状。结果 共有104例患者参加检测，32例患者的D-二聚体检测值494 ng/ml,其中16例患者经肺通气、灌注扫描V/Q证实为肺栓塞，VIDAS DD法的敏感性为100%，阴性预期值为100%。结论 VIDAS DD法可作为诊断栓塞的首选筛选方法。

    【关键词】肺栓塞；D-二聚体；酶联免疫吸附测定

    A rapid quantitative ELISA for measuring D-dimer to exclude pulmonary embolism

    MEI Ling.Department of Laboratory，the First People’s Hospital of Hebei458030,China

    【Abstract】 Objective To study new assay fulfill the repuive ments for diagnostic exclusinm in patients supected of pulmonary embolism.Methods Plasma D-dimer of dini cally suspected Pul monary embolism patients were measured by VIDAS D-Dimer,one year after their in dusion all patients were con firmed to know if they had any new symptoms suggestive of deep vein thrombosis or pulmonary embolism.Results Among 104 suspected pulmonary embolism patients,32 patients with DD levels494 ng/ml,16 patients were one of them with DD levels>494 ng/ml,the test showed a sensitivity of 100%,a negative predictive vale of 100%.Conclusion VIDAS D-dimer is well sited asdiagnostic tool for the exdusion Pulmonary embolism. ......