苯二氮卓受体对放射性脑损伤大鼠氧自由基的影响(2)
综上所述，在照射前使用地西泮通过增强SOD的活力，降低脑组织中MDA的含量，稳定了细胞膜和生物大分子，从而减轻自由基产生的继发性内源性损伤，而氟马西尼可拮抗地西泮的保护效果。说明在放射性脑损伤时自由基的损伤过程中苯二氮卓受体起着一定的调控作用。
参考文献
1 Olson JJ,Friedman R,Orr K,et al.Cerebral radioprotection by pentobarbital:dose-response characteristics and association with GABA agonist activity.J Neurosurg,1990,72:749-758.
2 谢红,王琛,徐府奇,等.地西泮对放射性脑损伤大鼠氧自由基的影响.临床麻醉学杂志,2007,23(01):53-54.
3 王琛，谢红，田野，等.清醒状态下大鼠放射性脑损伤实验模型的建立.苏州大学学报(医学版)，2004，24：455-458.
4 Siesjo BX,Zhal Q,Pahlmark K,et al.Glutamute,calcium and free radicals as mediators of ischemia brain damage.Amm Thorac surg,1995,59:1316-1320.
5 Ganasoundari A,Devi Pu.Modulation of glutathione and antioxidant emgymes by ocinum sanctum and its role in protection against radiation injury.Indian J Exp Biol,1999，37:262-268.
6 Sabitha KE,Shyamaladevi CS.Oxidant and antioxidant activity in patients with oral cancer and treated with radiotherapy.Oral Oncol,1999,35(3):273-277.
7 Regan MH,Song D,Vander Heide SJ,et al.Free radicals and the ischemia-evoked extracellular accumulation of amino acids in rat cerebral cortex.Neurochem Res,1997,22：273-280.
8 Musavi S，Kakkar P.Effect of diazepam treatment and its withdrawal on pro/antioxidative processes in rat brain.Mol Cell Biochem，2003,245:51-56., 百拇医药(刘 岗 谢 红 王 琛 徐府奇 田 野)
参考文献
1 Olson JJ,Friedman R,Orr K,et al.Cerebral radioprotection by pentobarbital:dose-response characteristics and association with GABA agonist activity.J Neurosurg,1990,72:749-758.
2 谢红,王琛,徐府奇,等.地西泮对放射性脑损伤大鼠氧自由基的影响.临床麻醉学杂志,2007,23(01):53-54.
3 王琛，谢红，田野，等.清醒状态下大鼠放射性脑损伤实验模型的建立.苏州大学学报(医学版)，2004，24：455-458.
4 Siesjo BX,Zhal Q,Pahlmark K,et al.Glutamute,calcium and free radicals as mediators of ischemia brain damage.Amm Thorac surg,1995,59:1316-1320.
5 Ganasoundari A,Devi Pu.Modulation of glutathione and antioxidant emgymes by ocinum sanctum and its role in protection against radiation injury.Indian J Exp Biol,1999，37:262-268.
6 Sabitha KE,Shyamaladevi CS.Oxidant and antioxidant activity in patients with oral cancer and treated with radiotherapy.Oral Oncol,1999,35(3):273-277.
7 Regan MH,Song D,Vander Heide SJ,et al.Free radicals and the ischemia-evoked extracellular accumulation of amino acids in rat cerebral cortex.Neurochem Res,1997,22：273-280.
8 Musavi S，Kakkar P.Effect of diazepam treatment and its withdrawal on pro/antioxidative processes in rat brain.Mol Cell Biochem，2003,245:51-56., 百拇医药(刘 岗 谢 红 王 琛 徐府奇 田 野)