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以中枢神经系统症状为首发表现的系统性红斑狼疮引发的思考(1)
http://www.100md.com 2009年5月5日 《中国实用医药》 2009年第13期
     【摘要】 目的 阐述系统性红斑狼疮中枢神经系统受累的临床特点,避免误诊误治。方法 通过病例分析探讨系统性红斑狼疮中枢神经系统受累的临床特点、发病机制及治疗方法。结果 所选病例除中枢神经系统表现外,还合并其他多系统损害,多种自身抗体阳性,抗生素治疗无效,对激素反应好。 结论 中枢神经系统症状可为系统性红斑狼疮的首发表现,应注意完善相关检查进行诊断与鉴别诊断,及时给予大剂量糖皮质激素治疗。

    【关键词】系统性红斑狼疮;中枢神经系统

    Systemic lupus erythematosus with central nervous system symptoms as its first manifestation

    ZENG Lin-juan,TENG Shu-ping,ZHONG Shu-ping,et al.Department of Hematology and Rheumatology,the Fifth Hospital of Sunsatsan University, Zhuhai,Guangdong 519000,China

    【Abstract】 Objective To expound characteristics of systemic lupus erythematosus(SLE)with central nervous system(CNS)involvements so as to avoid misdiagnosis and mistreatment.Methods Discuss clinical characteristics,pathogenesis and treatments of SLE through the analysis of cases.Results Besides CNS symptoms,the patient in our case also has multi-system damage,a variety of self-antibodies positive.There is no response to antibiotics and good response to the hormone.Conclusion CNS symptoms could be the first performance of SLE,doctors should carry out related inspections to improve the diagnosis and differential diagnosis and in a timely manner to give high-dose glucocorticoid treatment. ......
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