妥泰单药治疗小儿癫痫86例临床疗效观察(2)
第1页 |
参见附件(1440KB,2页)。
综上所述,正确诊断、及时用药、合理选药是控制癫痫发作的重要环节,而完全终止癫痫的发作却不损害患儿的生活质量则是临床抗癫痫治疗的最终目标。随着新型AEDs的相继问世,为临床有效控制难治性癫痫的发作带来了新的希望。癫痫对患儿的危害极大,有的可以影响一生,因此,减少发病率,增加治愈率,以保障儿童健康,提高生命质量,是我们医务工作者不可推卸的职责。
参考文献
[1] 安得仲.神经系统疾病鉴别诊断学.人民卫生出版社,2000:629-639.
[2] Shank RP,Gardocki JF,Streeter AJ,et al.An over-view of the preclinical aspects of topiramate:Pharmacology,phar-macokinetics,and mechanism of action.Epilepsia,2000,41(Suppl1):S3-S9.
[3] Herrero AI,Del olmo N,Gonzalez-Escalada JR,et al.Two new actions of topiramate:Inhibition ofdepolarizingGA-BA(A)-mediated responses and activation of a potassium con-ductance.Neuropharmacology,2002,42(2):210-220.
[4] French JA,Kanner A,Bautis J,et al.Efficacy and tolera-bility of the new antiepileptic drugs II:treatmentofrefractory epi-epsy:report of the Therapeutics and Technology AssessmentSubcommittee and Quality Standards Subcommittee of the Ameri-can Academy of Neurology and the American Epilepsy Society.Neurology,2004,62(8):1261-1273.
[5] 王艺,孙道开.小儿抗癫痫药物的不良反应.中国实用儿科杂志,2000,15(9):570-574.
您现在查看是摘要介绍页,详见PDF附件(1440KB,2页)。