喜炎平联合康复新液治疗手足口病临床观察(1)
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【摘要】 目的 观察喜炎平联合康复新液治疗手足口病的临床疗效。方法 将手足口病普通型患儿274例，随机分为治疗组,140例和对照组134例。两组均予以退热等对症支持治疗,合并细菌感染者给予抗生素治疗,治疗组给予喜炎平注射液静脉滴注,加用康复新液口服及外用；对照组给予病毒唑注射液静脉滴注,加用利多卡因、蒙脱石混悬液涂口腔,比较两组的临床症状改善情况及疗效。结果 治疗组总有效率高于对照组；治疗组口腔溃疡愈合、皮疹消退时间、进食改善至正常的时间、退热时间较对照组明显缩短(P<0.05)。结论 喜炎平联合康复新液治疗手足口病普通型,患儿依从性好，副作用小,安全有效。
【关键词】 手足口病；治疗；喜炎平；康复新液
The Clinical observation of Xiyanping combined with Kang fuxin liquid in treatment of hand foot and mouth disease FENG De,gang, YANG li,jun, CHEN Hua,ying. Department of Pediatrics, The Central Hospital of Guangyuan, Sichuan 628000,China
【Abstract】 Objective To observe the clinical curative effect of Xiyanping combined with Kangfuxin liquid treating hand foot mouth disease.Methods The foot and mouth disease in 274 children patients with the common type, were randomly divided into treatment group 140 cases and control group 134 cases. Two groups were to be antipyretic treatment, combined with bacterial infection to antibiotic treatment, the treatment group were treated with intravenous injection, with Kangfuxin liquid oral and topical,the control group was given Virazole injection intravenous drip, with lidocaine, montmorillonite suspension with oral, compared with two groups of clinical symptom improvement and effect. Results The treatment group total efficiency is higher than that of the control group,the treatment group cavity ulcer healing time, rash subsided, the feed improvement to the normal time, defervesce time than in the control group was significantly shorter(P<0.05). Conclusion Xiyanping combined with Kangfuxin liquid in treatment of hand foot and mouth disease common type, patient compliance is good, the side effect is small, safe and effective.
【Key words】 Hand foot mouth disease；Treatment；Xiyanping；Kangfuxin liquid
手足口病是由肠道病毒(以柯萨奇A组16型(CoxA16)、肠道病毒71型(EV71)多见)引起的急性传染病，主要症状表现为手、足、口腔等部位的斑丘疹、疱疹。少数病例可出现脑膜炎、脑炎、脑脊髓炎、肺水肿、循环障碍等，多由EV71感染引起，致死原因主要为脑干脑炎及神经源性肺水肿[1]。目前小儿手足口病尚无特效西药治疗,以中西医结合治疗的疗效最好,多采用对症治疗,临床症状缓解慢,多数患儿因口腔溃疡疼痛拒食,严重影响患儿生活质量。我科采用喜炎平注射液静脉滴注联合康复新液口服及外用治疗普通型手足口病取得了满意的疗效,现报告如下。
1 资料与方法
1.1 一般资料 2009年3至2011年6月本院儿科确诊手足口病患儿274例。将全部病例随机分为两组:治疗组140例,对照组134例 ......
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