女性冠心病危险因素的病例对照研究(2)
高尿酸血症是心血管疾病的危险因素，随着血糖的升高，心血管疾病的发病危险度明显增加。在美国NHANESⅢ[5]的研究项目表明血尿酸水平>357 mmol/L是冠心病的独立危险因素其主要原因是尿酸结晶增多沉积于动脉壁，损伤动脉内膜，尿酸还能促使血小板聚集，激活血小板，促使冠状动脉内血栓的形成。
综述所述，女性冠心病是有多重因素造成的，需要加强对女性人群多种可控危险因素的联合控制，如血脂异常、血糖、血压等才能对降低冠心病发病率起到积极作用。
参 考 文 献
[1] Mosca L， Appel LJ， Benjamin EJ， et al Evidencebased guidelines for cardiovascular disease prevention in women. Circulation，2004,109(5):672693.
[2] Ho PM， Magid DJ， Shetterly SM, et al Medication nonadherence is associated with abroad range of adverse outcomes in Patients with coronary artery disease. Am Heart J,2008,155(4):589590.
[3] Mitu F, Mitu M, Turiceanu M, et al Carotid atherosclerotic alterations revealed at ultrasonografic examination at patients with Coronary heart disease.Rev Med Chir Soc Med Nat Iasi,2005,109(2):236241.
[4] Mosca L, Carole L, Benjamin EJ, et al Evidencebased guidelines for Cardiovascular disease prevention in women 2007(update).Circulation,115:14811501.
[5] Poirier P, Lemieux, Maurlege P, et al Impact of waist circumference on the Relationship between blood Pressure and insulin: the Quebec Health Survey. Hypertension,2005,45(3):363367., 百拇医药(张哲)
综述所述，女性冠心病是有多重因素造成的，需要加强对女性人群多种可控危险因素的联合控制，如血脂异常、血糖、血压等才能对降低冠心病发病率起到积极作用。
参 考 文 献
[1] Mosca L， Appel LJ， Benjamin EJ， et al Evidencebased guidelines for cardiovascular disease prevention in women. Circulation，2004,109(5):672693.
[2] Ho PM， Magid DJ， Shetterly SM, et al Medication nonadherence is associated with abroad range of adverse outcomes in Patients with coronary artery disease. Am Heart J,2008,155(4):589590.
[3] Mitu F, Mitu M, Turiceanu M, et al Carotid atherosclerotic alterations revealed at ultrasonografic examination at patients with Coronary heart disease.Rev Med Chir Soc Med Nat Iasi,2005,109(2):236241.
[4] Mosca L, Carole L, Benjamin EJ, et al Evidencebased guidelines for Cardiovascular disease prevention in women 2007(update).Circulation,115:14811501.
[5] Poirier P, Lemieux, Maurlege P, et al Impact of waist circumference on the Relationship between blood Pressure and insulin: the Quebec Health Survey. Hypertension,2005,45(3):363367., 百拇医药(张哲)