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米非司酮联合甲氨蝶呤治疗不同血β-HCG浓度宫外孕的疗效观察(1)
http://www.100md.com 2012年7月25日 刘书鹏 姚虹 耿英
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     【摘要】 目的 探讨米非司酮联合甲氨蝶呤在治疗不同血β-人绒毛膜促性腺激素(β-HCT)值的宫外孕的疗效。方法 选取321例宫外孕住院患者,所有患者给予米非司酮联合甲氨蝶呤治疗。根据血β-HCG 浓度不同分组,β-HCG≤1000U/L为A组,1000U/L<β-HCG≤2000U/L为B组。β-HCG>2000U/L为C组,统计各组患者的治愈率,比较各组的差异。结果 321例患者,成功246例,总治愈率为76.6%。其中,A组56例,成功47例,治愈率为83.9%;B组176例,成功139例,治愈率为79.0%,C组89例,成功60例,治愈率为67.4%;A组与C组、B组与C组治愈率比较,差异有统计学意义。A组与B组治疗率比较,差异无统计学意义(P>0.05)。结论 米非司酮联合甲氨蝶呤治疗宫外孕疗效显著,在β-HCG ≤2000 U/L 时,效果更加明显。

    【关键词】 米非司酮;甲氨蝶呤;β-HCG;宫外孕

    Observation of curative effect on Mifepristone combined with Methotrexate in the treatment of patients with ectopic pregnancy in different concentration of blood β-HCG LIU Shu-peng, YAO Hong, GENG Ying.Department of Gynecology,The Poeple’s Hospital of Changji,Xinjiang 831100,China

    【Abstract】 Objective To observe the efficacy of Mifepristone combined with Methotrexate in the treatment of patients with ectopic pregnancy in different concentration of blood β-human chorionic gonadotropin (β-HCG). Methods 321 hospitalized patients with ectopic pregnancy were choose and all patients were taken oral Mifepristone combined with Methotrexate. According to different concentration of blood β-HCG, β-HCG≤1000U/L was group A, β-HCG>1000U/L and ≤2000U/L was group B, β-HCG>2000U/L was group C, the treatment effect and adverse reactions were summarized and the differences among all groups were compared. Results In 321 cases, 246 cases were healed, the total cure rate was 76.6%. In 56 cases of group A, 47 cases were healed, the cure rate was 83.9%.In 176 cases of group B, 139 cases were healed, the cure rate was 79.0%.in 89 cases of group C, 60 cases were healed, the cure rate was 67.4%.There was no significant difference between the group A and group B(P>0 ......

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