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新余市围产儿出生缺陷相关因素及产前诊断分析(1)
http://www.100md.com 2012年8月5日 邓红 袁小芳 胡香兰
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     【摘要】 目的 了解新余市出生缺陷的可疑因素及产前诊断现状,提出干预措施和提高产前诊断率的对策。 方法 回顾性统计新余市2001~2011年出生缺陷情况,分析出生缺陷率、出生缺陷发生顺住与构成比及产前诊断情况。 结果 72514例围产儿中,出生缺陷儿481例,出生缺陷发生率 66.33/万;随孕母年龄增加,围产儿的出生缺陷发生率升高( χ2 =45.63, P <0.05),35岁以上缺陷发生率明显增高( P <0.05);孕母文化程度越低,出生缺陷的发生机会越大(RR=4.59);出生缺陷围产儿死亡高于非出生缺陷围产儿(RR=16.21);产前诊断的出生缺陷儿有151例(31.39%)。 结论 新余市出生缺陷发生率偏高,产前诊断率偏低,提高产前诊断水平已是势在必行。

    【关键词】

    围产儿;出生缺陷;产前诊断;分析

    

    Analysis the related factors of brith defects and prenatal diagnosis among perinatal infants in Xinyu city

    DENG Hong,YUAN Xiao-fang,HU Xiang-lan.

    Department of Pediatric, Jiangxi province, Chinese Traditional Hospital of Xinyu,Xinyu 338025,China

    

    【Abstract】 Objective

    Elevating the strategy of prenatal diagnosis ratio based on the status of the risk factors of birth defects and prenatal diagnosis in Xinyu. Methods Retrospectively,analyzing the rate of birth defects,prenatal diagonosis information and the constituent ratio of birth defects between 2001 and 2011 in Xinyu. Results 27514 perinatal infants have 481 birth defects.The incidence of birth defects are 66.33/ million.With increasing maternal age, increased incidence of birth defects ( χ2 =45.63, P <0.05),defects in more than 35 years of age was significantly higher( P <0.05), maternal education level, the lower, the greater the incidence of birth defects(RR=4.59),birth defects in perinatal deaths higher than the non-birth defect perinatal (RR=16.21). 151 samples(31.39%) are birth defect infants through prenatal diagnosis. Conclusion The ineidenee of birth defects is high and the rate of prenatal diagnosis is low in the past.Improve the level of prenatal diagnosis is imperative ......

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