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天麻钩藤饮辨证加减治疗原发性高血压伴失眠症77例临床疗效观察(1)
http://www.100md.com 2018年3月5日 《中国实用医药》 2018年第7期
     【摘要】 目的 分析天麻钩藤饮辨证加减治疗原发性高血压伴失眠症的临床疗效。方法 77例原发性高血压伴失眠症患者作为观察组, 71例原发性高血压伴失眠症患者作为对照组。观察组予以天麻钩藤饮辨证加减治疗, 对照组口服苯磺酸氨氯地平和艾司唑仑治疗。比较两组患者治疗前后睡眠状况、血压变化情况。结果 治疗前, 兩组患者匹兹堡睡眠质量指数(PSQI)评分和血压水平比较, 差异无统计学意义(P>0.05)。治疗后, 两组PSQI评分均低于治疗前, 且观察组PSQI评分(7.92±3.91)分低于对照组的(10.03±4.47)分, 差异有统计学意义(P<0.05)。治疗后, 两组患者血压水平均低于治疗前, 差异有统计学意义(P<0.05)。治疗后, 两组患者血压水平比较, 差异无统计学意义(P>0.05)。结论 天麻钩藤饮辨证加减治疗原发性高血压伴失眠症不仅可改善患者睡眠情况, 还可降低血压, 疗效确切。

    【关键词】 天麻钩藤饮;原发性高血压;辨证加减;失眠症

    DOI:10.14163/j.cnki.11-5547/r.2018.07.057

    【Abstract】 Objective To analyze the clinical efficacy of Tianma Gouteng drink by syndrome differentiation of addition and subtraction in the treatment of primary hypertension complicated with insomnia. Methods There were 77 patients with primary hypertension complicated with insomnia as observation group, and 71 patients with primary hypertension complicated with insomnia as control group. The observation group was treated with Tianma Gouteng drink by syndrome differentiation of addition and subtraction, and the control group was treated with amlodipine besylate and estazolam by administration. Comparison were made on sleep condition and blood pressure before and after treatment between the two groups. Results Before treatment, both groups had no statistically significant difference in Pittsburgh sleep quality index (PSQI) score and blood pressure level (P>0.05). After treatment, both groups bad lower PSQI score than before treatment, and the observation group had lower PSQI score as (7.92±3.91) points than (10.03±4.47) points in the control group. Their difference was statistically significant (P<0.05). After treatment, both groups had lower blood pressure level than before treatment, and the difference was statistically significant (P<0.05). After treatment, both groups had no statistically significant difference in blood pressure level (P>0.05). Conclusion Tianma Gouteng drink by syndrome differentiation of addition and subtraction in treating primary hypertension complicated with insomnia shows affirmative efficacy, and can not only improve sleep condition, but also lower blood pressure.

    【Key words】 Tianma Gouteng drink; Primary hypertension; Syndrome differentiation of addition and subtraction; Insomnia

    高血压病是常见的心脑血管疾病, 是失眠障碍的一个重要的诱因。失眠是常见的睡眠障碍表现之一, 原发性高血压患者合并失眠的发生率高达50%以上, 可表现为入睡困难, 睡眠浅易觉醒及白天嗜睡。失眠又可引起患者血压升高, 加重高血压疾病的病情, 严重影响患者的身心健康和生活质

    量[1]。目前西医多以对症治疗为主。中医认为, 高血压和失眠病因相同、病机相通, 可根据辨证分型进行异病同治。选取2016年3月~2017年10月本中心77例采用天麻钩藤饮辨证加减治疗原发性高血压伴失眠症患者进行研究, 现总结如下。, http://www.100md.com(吴清 周雯睿 陆佳)
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