病毒性脑炎血清心肌酶的变化及其临床意义(1)
 |
| 第1页 |
参见附件(1415KB，2页)。
【摘要】目的研究病毒性脑炎时血清心肌酶的变化及其临床意义。 方法收集病毒性脑炎(病脑组)48例,另有体检正常者40例为对照组。采用东芝全自动生化分析仪,以酶速率法测定所有患者的血清天冬氨酸转氨酶(AST)、乳酸脱氢酶(LDH)、肌酸激酶(CK)、肌酸激酶心肌型同工酶(CKMB)、a羟丁酸脱氢酶(aHBDH)水平。结果62.5%(30/48)病脑组血清心肌酶出现异常,与对照组比较差异有统计学意义(P<0.01);病脑组患者血清中AST、LDH、CK水平明显高于对照组(P<0.05或<0.01),病脑组CKMB、aHBDH水平与对照组比较,差异无统计学意义(P>0.05)。结论病毒性脑炎常伴随心肌细胞损伤,血清心肌酶水平升高,对该类患者应常规行血清心肌酶测定。
【关键词】
脑炎; 病毒性; 脑膜; 肌酸激酶;L乳酸脱氢酶
Changes and clinical significance of serum myocardial enzymes in patients with viral encephalitis
ZHANG Xiuqing,SONG Bindong,DING Yinyong,et al.The Second Hospital of Liaocheng Affiliated to Taishan Medical College,Linqing,Shan Dong province 252600,China
【Abstract】ObjectiveTo explore the changes and clinical significance of serum myocardial enzymes in patients with viral encephalitis.MethodsFortyfive patients suffering from virus encephalitis(virus encephalitisgroup)were collected.Besides,40 health subjects served as control group.Serum aspartate aminotransferase(AST),lactate dehydrogenase(LDH),creatine kinase(CK),muscle heartacid kinase is oenzyme(CKMB),Ahydro xybutyric acid dehydrogenase(AHBDH)of the patients were examined by TOSHIBA automaticbio chemical analyzer and enzymerate assay.Resultsthe myocardial enzyme level of 62.5%(30/48)of virus encephalitis group changed significantly compared with that of control group(P<0.01);serum AST,LDH,CK levels of The myocardial enzymes of patients with cerebral functional disorder were significantly Higher than those of patients with normal cerebral function(P<0.05 or<0.01).There were no significant differences in the levels of CKMB,AHBDH of virus encephalitis group compared with those of control group(P>0.05).ConclusionVirus encephalitis is associated with myocardial injury,increased serum myocardial enzyme level.So,those patients should be measured of their routinely myocardial enzymes in the serum.
【Key words】
Encephalitis; Viral;Meningeal; Creatinekinase; Llactatedehydrogenase
病毒性脑炎是小儿中枢神经系统感染常见的类型,在小儿神经系统疾病中占有重要地位。病毒直接感染或感染后的变态反应,引起神经组织的炎症水肿及神经细胞变性坏死,血管和血管周围损伤及其所造成的供血不足[1],临床主要表现为感染中毒症状及颅内高压,部分患儿也可有神经系统外的临床表现 ......
您现在查看是摘要介绍页，详见PDF附件(1415KB，2页)。