早期氧疗联合左侧卧位对新生儿HIE影响及随访研究(1)
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【摘要】 目的 探讨早期氧疗联合左侧卧位对新生儿HIE的影响及随访。方法 对123例37~40周孕妇,随机分为观察组63例,对照组60例。观察组入院后在常规监护及心理安慰基础上,给予待产孕妇吸氧2 L/min、2次/d、30 min/次,并配合左侧卧位,分娩时产程给氧及生后新生儿吸氧30 min;对照组60例常规监护及心理安慰,据观察情况对症处理。结果 两组新生儿Apgar评分1、5 min比较,有显著性差异(P<0.01);两组新生儿生后NBNA各项评分比较,有显著性差异(P<0.05、P<0.05)。对3、6、12、18、24、72、84、96个月智能发育商(DQ)比较,观察组明显高于对照组(P<0.01);神经系统后遗症发病率比较,观察组明显低于对照组(P<0.05)。结论 待产孕妇早期给氧联合左侧卧位对新生儿,能减轻脑灌注损伤,减少后遗症,提高儿童的生存质量及人口素质。
【关键词】 新生儿;氧疗;HIE;卧位;随访
Early reoxygenation joint left lying on neonatal HIE and follow-up study
LV Yan,FU Xing-gen.Chinese Medicine Hospital of Tengzhou,Shandong,Tengzhou 277500,China
【Abstract】 Objective To explore the early reoxygenation and lying on the left side of neonatal HIE and follow-up study.Methods 123 cases of active movement in the 37~40 week pregnant women divided into two groups under the voluntary 63 cases,60 cases of the control group.Observer Group in the conventional care,nutrition and psychological comfort,based on early to give pregnant women oxygen 2 L/min,2 times/day,30 mins/times,and in line with the left side lying,birth process oxygen and oxygen after birth,the newborn 30 minutes.Control group were given conventional measure of conventional care and mental psychological comfort,it was observed to deal with the situation of illness.Results Two groups of neonatal Apgar score 1 min,5 min comparison,the difference was significant(P<0.005,P<0.01);two groups of neonatal after birth NBNA the score comparison,the difference was significant(P<0.005 or P<0.05).3,6,12,18,24,72,84,96 intelligent months from the development quotient(DQ)of comparison,significantly higher than those in the observation group(P<0.01);the incidence of nervous system sequelae of comparison,the observation group were significantly lower in the control group(P<0.05).Conclusion Early oxygen and left lying on the impact of neonatal HIE,can reduce the cerebral reperfusion injury and reduce side effects,improve the quality of life of children and the quality of the population.
【Key words】 Newborn; Oxygen therapy; HIE; Supine; Follow-up study
新生儿缺氧缺血性脑病(HIE)是新生儿窒息后的严重并发症,病情重,病死率高,并可产生永久性神经系统功能障碍,如智力低下、癫痫、脑性瘫痪和共济失调等[1] ......
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