未生育女性卵巢早衰18例临床分析
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[摘要] 目的 通过对未生育妇女卵巢早衰患者进行周期治疗和促排卵治疗,评价其疗效,探讨可能有效的促排卵方案。方法 对18例患者行雌孕激素周期治疗3～6个周期,观察治疗前后临床症状、血清激素水平,并采用三种方法促排卵治疗。结果 18例患者经雌孕激素治疗3～6周期后血清卵泡刺激素(FSH)、黄体生成素(LH)水平明显下降,血清雌二醇(E2)升高不明显,以人绝经期促性腺激素HMG/人绒毛期促性激素的素(HCG)方案和促性腺激素释放激素激动剂(GnRH-a)/HMG/HCG方案促排卵治疗有成熟卵泡发育,有1例妊娠。结论 卵巢早衰患者尽可能查明病因,针对病因治疗,并尽早行激素周期治疗,有利于促排卵成功:(GnRH-a)/HMG/HCG具有可行性。
[关键词] 卵巢早衰: 激素周期治疗; 促排卵方案
[中图分类号] R711.75 [文献标识码] A [文章编号] 1673-9701(2010)07-147-02
The Clinical Analysis of 18 Nulliparous Women with Premature Ovarian Failure
ZHUANG Weihong1 GE Desheng2
1.HuaiBei Mining Industry Group General Hospital,Huaibei 235000,China;2.TCM Hospital of Huaibei City,Huaibei 235001,China
[Abstract] ObjectiveTo evaluate the efftct of hormone therapy(HT) and sequently inducing ovulation treatment in nulliparous women with the premabure ovarian failure(POF),and to explore the possible effective ovulation inducing scheme. Methods18 patients with POF were treated by HT for three to six cycles,the clinical symptoms,serum sex-homone levels,were obserred before and after treatment,Meantime,three schemes of ovarian inducing protocols were applied in these patients ......
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