吉西他滨单药治疗老年晚期非小细胞肺癌的临床观察
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[摘要] 目的 观察吉西他滨单药治疗老年晚期非小细胞肺癌(NSCLC)的临床疗效和不良反应。方法 36例晚期NSCLC初治老年患者予吉西他滨1000mg/m2第1、8天静脉滴注30min,21d为1个周期,治疗2～4个周期,每2个周期评价疗效。结果 完全缓解(CR)1例,部分缓解(PR)11例,稳定(SD)10例,进展(PD)14例,总有效率(CR+PR)33.4%,疾病控制率(CR+PR+SD)为61.2%。主要毒副反应为骨髓抑制和血小板减少。结论 吉西他滨单药治疗老年晚期NSCLC有效,耐受性好。
[关键词] 吉西他滨; 晚期非小细胞肺癌; 老年患者
[中图分类号] R734.2 [文献标识码] A [文章编号] 1673-9701(2010)13-139-02
Clinical Observation of Gemcitabine in Treating Advanced Non-small Cell Lung Cancer in the Elderly Patients
WANG Yongshun WANG Yantao JI Xuehua
The Eighth Hospital of Qingdao,Qingdao 266100,China
[Abstract] ObjectiveTo evaluate the clinical efficacy and side effects of gemcitabine as single chemotherapy for elderly patients with advanced non-small-cell lung cancer(NSCLC). MethodsThirty-six elderly patients with advanced NSCLC who were chemotherapy-naivere enrolled in this study ......
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