中西医结合治疗溃疡性结肠炎的临床研究
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[摘要] 目的 评价中西医结合治疗溃疡性结肠炎的疗效。方法 将90例溃疡性结肠炎患者分为对照组和观察组。对照组：柳氮磺胺吡啶片口服，注射用氢化可的松琥珀酸钠加生理盐水作保留灌肠；观察组：在对照组用药方式的基础上，加用中药方剂保留灌肠，同时口服中药汤剂。结果 观察组显效率73.33%(33/45)高于对照组显效率48.89%(22/45)，差异具有显著性(P<0.05)；观察组总有效率100.00%(45/45)高于对照组总有效率86.67%(39/45)，差异具有显著性(P<0.05)。两组均未见明显不良反应。结论 中西医结合治疗溃疡性结肠炎疗效可靠，安全性高。
[关键词] 溃疡性结肠炎；柳氮磺胺吡啶；氢化可的松；灌肠；中药
[中图分类号]R574.62 [文献标识码] B[文章编号]1673-9701(2011)19-159-02
Effects Observation of Combining Traditional Chinese and Western Medicine in Treatment of Ulcerative Colitis
ZHANG Guorong
Nanxun Hospital of Combined Traditional Chenese and Western Medicine, Huzhou City in Zhejiang Province, Huzhou 313009, China
[Abstract] Objective To evaluat of efficacy of combining traditional Chinese and Western medicine in treatment of ulcerative colitis. Methods Nintypatients with ulcerative colitis were divided into control group and observation group. Control group: sulfasalazine tablet, injection of hydrocortisone sodium succinate plus saline, as retention enema.observation group: treatment methods in the control group, plus Chinese proprietary retention enema, and oral medicine decoction. Results Markedly effective rate was 73.33% (33/45)in observation group ,it were higher than 48.89% (22/45) in control group with there was a significant difference (P<0.05), the total efficiency was 100.00% (45/45)in observation group ,it was higher than 86.67% (39/45) in control group with there was a significant difference(P<0.05)No significant adverse effects in both groups. ConclusionCombining traditional Chinese and Western medicine treatment of ulcerative colitis good efficacy，and safe.
[Key words] Ulcerative colitis；Sulfasalazine；Hydrocortisone sodium succinate；Enema；Chinese medicine
溃疡性结肠炎是一种原因不明的局限于结肠黏膜及黏膜下层的内科炎症，病程漫长，并常反复发作[1]。本研究中，笔者采用中西医结合治疗了45例溃疡性结肠炎患者，结果疗效满意，现报道如下。
1对象和方法
1.1 研究对象
选择2008年10月～2010年10月在本院就诊的溃疡性结肠炎[2]患者90例，其中男49例，女41例，年龄17～67岁，随机分成观察组和对照组。观察组45例中男25例，女20例，平均年龄(37.2±12.6)岁，轻型19例(42.22%)、中型17例(37.78%)、重型9例(20.00%)；对照组45例中男24例，女21例，，平均年龄(36.7±13.8)岁，轻型18例(40.00%)、中型18例(40.00%)、重型9例(20.00%)。两组患者的年龄、病情轻重等一般资料差异不显著，具有可比性。
1.2方法
对照组：柳氮磺胺吡啶片(上海三维制药，国药准字H31020450)，口服， 1g/次，4次/d；注射用氢化可的松琥珀酸钠 (烟台北方制药 ......
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