咪达唑仑联合有创机械通气治疗老年急性重症左心衰竭疗效观察(1)
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[摘要] 目的 探讨咪达唑仑联合有创机械通气治疗老年急性重症左心衰竭的疗效。方法 35例老年急性重症左心衰竭患者在常规治疗基础上应用咪达唑仑联合有创机械通气治疗，比较治疗前后患者的心率、呼吸频率、平均动脉压、尿量变化及血气分析变化。结果 治疗后患者的心率、呼吸频率、平均动脉压、尿量均较入院时明显改善，差异有统计学意义(P<0.05)。治疗前后的血气分析值各项指标比较差异均有统计学意义(P<0.05)。结论 老年急性重症左心衰竭患者应尽早进行咪达唑仑联合有创机械通气治疗，可以有效缓解患者的肺水肿、呼吸衰竭症状，改善呼吸功能，提高抢救成功率，因此值得临床推广应用。
[关键词] 咪达唑仑；机械通气；急性重症左心衰竭
[中图分类号] R541 [文献标识码] B [文章编号] 1673-9701(2011)25-97-02
Effect of Midazolam Combined with Invasive Mechanical Ventilation in Treatment of Elderly Patients with Severe Acute Left Heart Failure Curative
GAOYuangen
Department of ICU，Central Hospital of Conghua City in Guangdong Province，Conghua510900，China
[Abstract] Objective To explore the effect of Midazolam combined with invasive mechanical ventilation in treatment of elderly patients with severe acute left heart failure curative. Methods All 35 senile patients in the treatment of general application on the basis of Midazolam combined with invasive mechanical ventilation ， compared heart rate， respiratory rate and mean arterial pressure， urine output changes and changes of blood gas analysis before and after treatment.ResultsHeart rate， respiratory rate and mean arterial pressure and urine volume is considerably improved than admission，there were significant differences between them(P<0.05).There were significant differences in Blood gas analysis value indicators before and after treatment(P<0.05). ConclusionPatients with severe acute left heart failure Should treated by mechanical ventilation combined with Midazolam sedation elderly，which can effectively alleviate symptoms in patients with pulmonary edema， respiratory failure， improving respiratory function， improve treatment success rate，so it's worth clinical application.
[Key words] Midazolam; Mechanical ventilation; Acute left heart failure curative
急性左心衰竭(acute left heart failure)是由于心脏瓣膜疾病、心肌损害、心律失常、左室前后负荷过重导致的急性心肌收缩力下降、左室舒张末期压力增高、排血量下降，从而引起以肺循环淤血为主的缺血缺氧、呼吸困难等临床症候群。急性肺水肿是最主要表现，可发生心源性休克或心搏骤停[1-2]。此病是内科常见的急危重症，大多数患者为老年人，特点是病史长、引起心衰的疾病种类较多、死亡率高，一旦患病需及时抢救。我科于2009年1月～2011年5月对35例老年急性重症心衰患者应用咪达唑仑联合有创机械通气治疗，取得了良好的疗效，现报道如下。
1 资料与方法
1.1 一般资料
选择我科2009年1月～2011年5月收治的35例老年急性重症心衰患者 ......
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