心踝血管指数对老年冠心病的早期诊断意义(1)
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[摘要] 目的 探讨心踝血管指数(CAVI)对老年冠心病的早期诊断意义。 方法 104例老年患者根据冠状动脉造影分为冠心病和非冠心病组，分别检测血压(BP)、空腹血糖(FBG)、甘油三酯(TG)、总胆固醇(TC)、体重指数(BMI)，并在1周内采用VaSera VS-1000血压脉搏测量装置检测CAVI。 结果 两组患者的年龄、性别、BMI、BP、FBG、TG、TC差异均无统计学意义(P>0.05)，冠心病组CAVI值较非冠心病组明显增高，差异有统计学意义(P<0.05)。 结论 老年冠心病患者动脉僵硬度明显增高，CAVI增高，CAVI对老年冠心病的早期诊断有一定的临床意义。
[关键词] 心踝血管指数；老年；冠心病；冠状动脉造影
[中图分类号] R541.4 [文献标识码] B [文章编号] 1673-9701(2011)33-144-03
The Role of Cardio-ankle Vascular Index in Early Diagnosis of Coronary Heart Disease
SHOU Xiaoling REN Aihua WANG Bozhong ZHU Liyue
Department of Cardiac Rehabilitation, Zhejiang Hospital, Hangzhou 310013, China
[Abstract] Objective To evaluate the significance of the cardio-ankle vascular index (CAVI) for early diagnosis of coronary heart disease(CHD). Methods All of 104 elderly patients were divided into CHD group and non-CHD control group according to coronary angiography result. The CAVI was detected within a week by VaSera VS-1000 blood pressure pulse measuring device, and blood pressure, fasting blood sugar, triglyceride, total cholesterol , body mass index were also measured. Results There were no significantly difference in age, gender, body mass index, blood pressure, fasting blood sugar, triglyceride and total cholesterol between two groups(P>0.05). However, the CAVI values in coronary heart disease group was higher than that of non-CHD group with a statistically significant difference(P<0.05). Conclusion Arterial stiffness in elderly patients with coronary heart disease was significantly higher, CAVI increased, CAVI has clinical significancfore in the elderly the early diagnosis of coronary heart disease.
[Key words] Cardio-ankle vascular index (CAVI) ;Elderly; Coronary heart disease; Coronary angiography
随着经济的发展，我国动脉粥样硬化的发病率日趋增加。冠心病(coronary heart disease, CHD)是动脉粥样硬化导致器官病变的最常见类型，多发生于中老年人。老年冠心病患者的死亡率较高，据统计，85%以上的冠心病死亡发生于65岁以上人群中。因此，对动脉结构和功能的异常进行及时准确的评价对于急性心血管事件的防治极为重要。Rotterdam研究[1]提示动脉僵硬度和动脉粥样硬化有强相关性，而动脉粥样硬化是心血管病危险的独立预测因子。
心踝血管指数(cardio ankle vascular index, CAVI)是一项新的不依赖血压的动脉硬化评价指标[2] ......
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