强化健康教育对糖耐量异常患者转归的影响(1)
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[摘要] 目的 研究强化健康教育对糖耐量异常患者转归的影响。 方法 采用随机单盲对照法，将体检中心检出的116例糖耐量异常患者分为强化教育(IE)组和一般教育(GE)组，每组患者于入组时以及随访1年时检测体重指数(BMI)、空腹血糖(FPG)、OGTT 2h血糖(OGTT 2hPG)、糖化血红蛋白(HbA1c)指标，进行组内前后及同期组间比较，统计转变为糖耐量正常、糖尿病的例数并进行组间比较。 结果 IE组BMI、FPG、OGTT 2hPG、HbA1c指标明显优于GE组(P<0.05)。糖耐量正常转化率有显著性增高(P<0.05)，糖尿病转化率有显著性降低(P<0.01)。 结论 强化教育可以增加糖耐量异常患者糖耐量正常转化率，可以降低糖耐量异常患者糖尿病转化率。
[关键词] 糖耐量异常；强化教育；疾病转归
[中图分类号] R587.1 [文献标识码] C [文章编号] 1673-9701(2012)01-125-02
Effect of intensive education on the outcome of the patients with impaired glucose tolerance
PAN Xiaoyun WANG Xingmin JI Haifeng CHEN Weiyan PAN Xiuwei
Department of Internal Medicine, Ruian Hospital of Traditional Chinese Medicine in Zhejiang Province, Ruian 325200, China
[Abstract] Objective To study the effect of intensive education on the outcome of patients with impaired glucose tolerance (IGT). Methods With the randomized single-blind control methods, 116 patients with impaired glucose tolerance were divided into the group with intensive education (IE) and the group with general education (GE) . Body mass index (BMI) , fasting glucose (FPG), 2-hour post oral glucose of oral glucose tolerance test (OGTT 2hPG) , glycated hemoglobin (HbA1c) were detected from each group in the time of beginning and following-up one year. The indexes of each group were compared，and the conversion rate of IGT to NGT and the conversion rate of IGT to diabetes in two groups were also compared. Results BMI, FPG, OGTT 2hPG, HbAlc were significantly lower in IE group than in GE group (P<0.05) , and the conversion rate of IGT to normal glucose tolerance (NGT) was significantly higher in IE group than in GE group (P<0.05) . The conversion rate of IGT to diabetes was significantly lower in IE group than in GE group (P<0.01). Conclusion Intensive education could increase the conversion rate of IGT to NGT and decrease the conversion rate of IGT to diabetes.
[Key words] Impaired glucose tolerance; Intensive education; Disease outcome
众所周知，目前糖尿病暴发流行，已成为继肿瘤、心血管病之后第三位危害人类健康的疾病[1]。糖尿病大多数都是从糖尿病前期发展而来，糖尿病前期是指血糖水平高于正常，但尚不能诊断为糖尿病状态，又称糖调节受损(IGR) ......
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