三种方法治疗小儿支气管哮喘的临床对比分析(1)
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[摘要] 目的 比较三种方法治疗小儿支气管哮喘的临床疗效。 方法 90例支气管哮喘患儿随机分为A组、B组及C组，每组各30例。A组予以孟鲁司特钠咀嚼片治疗，B组予以氨茶碱片治疗，C组予以酮替酚片治疗，治疗2个月后，观察比较三组患儿的临床疗效、症状缓解及消失时间，随访半年，观察各组复发情况及复发时间。 结果 A组、B组及C组临床有效率分别为93.33%、80.00%及66.67%，三组相比差异有统计学意义(P<0.05)；A组患儿症状缓解及消失时间均明显短于B、C组(P<0.05)；且A组复发率低于B、C组，复发时间晚于B、C组(P<0.05)。 结论 孟鲁司特钠治疗小儿支气管哮喘疗效较佳，症状改善所需时间短，且复发率低、间隔时间长，临床可广泛应用。
[关键词] 孟鲁司特钠；氨茶碱；酮替酚；小儿支气管哮喘
[中图分类号] R562.25 [文献标识码] B [文章编号] 1673-9701(2012)01-152-02
Clinical comparative analysis of three methods for treatment with the children with bronchial asthma
WANG Rongshan JIN Hongxing
Department of Pediatrics Zhejiang Province Yiwu City MCH，Yiwu 322000, China
[Abstract] Objective To compare the clinical efficacy of three methods for treating with the children with bronchial asthma. Methods All of 90 patients with bronchial asthma were randomly divided into group A, group B and group C, and each group had 30 cases, group A was given montelukast sodium chewable tablets, group B was given aminophylline tablets, and group C was received ketone tablets, after two months, the clinical efficacy, symptoms easing and disappearing time were compared in the three group; all of the children were followed up for 6 months, the recurrence situation and time were observed. Results The clinical efficiency of group A, group B and group C were 93.33%, 80.00% and 66.67%, there were significant differences in the three groups (P<0.05). The symptoms easing and disappearing time in group A were significantly shorter than group B and group C, the three groups had significantly differences (P<0.05). And the recurrence rate in group A was lower than group B and group C, the recurrence time is shorter than group B and group C (P<0.05). Conclusion Montelukast sodium has good efficacy to treat with the children with bronchial asthma, short symptom improvement time, and the recurrence rate is low, interval time is long, and it can be widely applied in clinical.
[Key words] Montelukast sodium; Aminophylline; Ketotifen; Children with bronchial asthma
支气管哮喘(bronchial asthma,BA)是一种由多种细胞参与的慢性气道炎症性疾病，其中小儿支气管哮喘在儿科较为常见 ......
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