保列治与哈乐佐助URSL治疗前列腺增生并膀胱结石20例(1)
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[摘要] 目的 评价保列治与哈乐佐助气压弹道碎石(ureteroscopic lithotripsy，URSL)治疗Ⅱ度前列腺增生并膀胱结石的疗效。 方法 40例Ⅱ度前列腺增生并膀胱结石患者随机分为观察组和对照组。对照组：采用URSL及前列腺电切汽化治疗；观察组：采用保列治与哈乐佐助URSL治疗。 结果 治疗后两组患者IPSS评分、Qmax、前列腺体积均明显改善(P < 0.01)。观察组总副作用率为10.00%，低于对照组(55.00%)，差异有统计学意义(P < 0.01)。 结论 保列治与哈乐佐助URSL治疗Ⅱ度前列腺增生并膀胱结石患者疗效可靠，而且可以避开手术的危害，副作用小。
[关键词] 前列腺增生；膀胱结石；气压弹道碎石；保列治；哈乐
[中图分类号] R697.32 [文献标识码] B [文章编号] 1673-9701(2012)04-0086-02
Study of Finasteride joint Tamsulosin sasuke URSL treatment 20 cases benign prostatic hyperplasia with bladder stones
YANG Hao WANG Yongwei XU Zengbao
Department of Urology, TCM of Huzhou City in Zhejiang Province, Huzhou 313000, China
[Abstract] Objective To study and analyze the efficacy that Finasteride joint Tamsulosin sasuke URSL treatment of Ⅱ degree benign prostatic hyperplasia with bladder stones. Methods All of 40 patients Ⅱ degree benign prostatic hyperplasia with bladder stones were divided into the observation group and the control group. The control group: treatment used URSL and TUVP. The observation group: treatment used Finasteride joint Tamsulosin sasuke URSL. Results After treatment, IPSS score, Qmax, prostate volume of patients of two groups obviously changed than before theatment (P < 0.01). The total rate of side effects of the observation group was 10.00%，and was lower than the control group (55.00%), the difference was significant (P < 0.01). Conclusion The effect is good that Finasteride joint Tamsulosin sasuke URSL treatment of Ⅱ degree benign prostatic hyperplasia with bladder stones,and can avoid the dangers of surgery,side effects are minor.
[Key words] Benign prostatic hyperplasia; Bladder stones; Ureteroscopic lithotripsy; Finasteride; Tamsulosin
良性前列腺增生是中老年男性常见病之一，发病率随年龄的增长而增加，而膀胱结石为前列腺增生常见并发症[1]。宇洪涛等[2]探讨前列腺增生并膀胱结石的有效治疗方法，结果表明输尿管镜下气压弹道碎石(ureteroscopic lithotripsy，URSL)和汽化电切是治疗前列腺增生并膀胱结石的一种安全有效的方法。但中老年患者基础疾病较多，围手术期风险大。井汉国[3]研究药物治疗良性前列腺增生症的合理方案，结果认为药物治疗良性前列腺增生，6个月内可联合应用保列治与哈乐，6个月后可单独应用保列治。本研究中，笔者在URSL的基础上，加用保列治与哈乐治疗Ⅱ度前列腺增生并膀胱结石患者，取得满意疗效，现报道如下。
1 资料与方法
1.1 病例选择
纳入标准：前列腺增生Ⅱ度，国际前列腺症状评分(IPSS)8～19分(0～7分显示轻度症状，8～19分中度症状，20～35分重度症状)；膀胱结石直径1.0～5.0 cm，符合URSL适应证。排除标准：合并有肝、肾功能不全等严重危及生命的疾病、拒绝URSL、遵医行为不佳、妊娠及精神病患者 ......
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