甲状腺癌与甲状腺结节钙化的关系探讨
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[摘要] 目的 探讨甲状腺结节钙化与甲状腺癌的关系。 方法 选择2009年1月～2012年1月683例因甲状腺结节在我院进行手术治疗的患者，回顾性分析这些患者的临床资料，总结甲状腺癌患者结节钙化的发生率及临床特点。 结果 恶性患者钙化和微钙化的比例显著高于良性患者，差异有统计学意义(P < 0.01)。微钙化对甲状腺癌的灵敏度为54.5%，阳性预测值为66.5%，特异性为89.5%。不同性别之间钙化的发生率无差异(P > 0.05)，<45岁的患者钙化和微钙化的发生率较高。 结论 甲状腺结节钙化，尤其是微钙化，对诊断甲状腺癌具有重要意义。[关键词] 甲状腺癌；甲状腺结节；钙化[中图分类号] R736.1
[文献标识码] B
[文章编号] 1673—9701(2012)23—0038—02Relationship between thyroid carcinoma and thyroid nodules with calcificationZHONG KaiDepartment of General Surgery， Nansha District TCM Hospital of Guangzhou City， Guangzhou
511462， China[Abstract] Objective To discuss the relationship between thyroid carcinoma and thyroid nodules. Methods Selected 683 cases with thyroid nodules from January 2009 to January 2012， clinical data were analyzed. Incidence of thyroid nodules with calcification and clinical features in thyroid carcinoma were concluded. Results Incidence of thyroid nodules with calcification and microcalcification in thyroid carcinoma were higher than benigh cases (P < 0.01). Sensitivity of microcalcification for thyroid carcinoma was 54.5%， positive predictive value was 66.5%， specificity was 89.5%. Incidence of calcification between different gender had no significant difference (P > 0.05). Incidence of calcification and microcalcification between aged <45 were higher. Conclusion Thyroid nodules with calcification， especially microcalcification， posses significance in diagnosis of thyroid carcinoma.[Key words] Thyroid carcinoma； Thyroid nodules； Calcification
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