钬激光与TURBT治疗浅表性膀胱癌的对照研究(1)
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[摘要] 目的 比较经尿道钬激光和经尿道电汽化治疗浅表性膀胱癌的效果，为临床最佳治疗方案提供依据。 方法 将70例浅表性膀胱癌患者随机分为两组，分别采用经尿道钬激光(实验组，n = 35)和经尿道电汽化(对照组，n = 35)治疗。比较两组治疗效果。 结果 两组患者手术时间、复发率、治愈率比较，差异无统计学意义(P > 0.05)。实验组术中出血和并发症发生率明显低于对照组，差异有统计学意义(P < 0.05)。 结论 经尿道钬激光治疗浅表性膀胱癌具有安全、有效、并发症少等特点，值得临床推广。
[关键词] 表浅性膀胱癌；钬激光；并发症
[中图分类号] R737.14 [文献标识码] B [文章编号] 1673—9701(2012)25—0153—02
Comparative study of transurethral holmium laser resection and standard transurethral electroresection (TURBT) in treating primary nonmuscle—invasive bladder cancer
HUANG Jianrong LIU Tairong SONG Leming GUO Shulin ZHONG Jiuqing DU Chuance
Department of Urology， the People's Hospital of Ganzhou City in Jiangxi Province， Ganzhou 341000， China
[Abstract] Objective To compare the efficacy of transurethral holmium laser resection for primary nonmuscle—invasive bladder cancer (HoLRBT) versus standard transurethral electroresection (TURBT). Methods Seventy patients with primary nonmuscle—invasive bladder cancer were randomly divided into two groups. The experimental group were treated with HoLRBT (n = 35) while the patients in control group were treated with TURBT using electricity vaporization. The intraoperative and postoperative characteristics of the HoLRBT and TURBT groups were compared. Recurrence and cure rates were also compared. Results There was no significant difference in operative time， recurrence rate， and cure rate between the two groups (P > 0.05). There were significant less intraoperative bleeding amount and incidence rate of complications in HoLRBT group with significant difference， compared to TURBT group (P < 0.05). Conclusion HoLRBT is a safe and effective approach for the management of primary nonmuscle—invasive bladder cancer， warranting an extensive use clinically.
[Key words] Primary nonmuscle—invasive bladder cancer； Holmium laser； Complication
膀胱癌在泌尿系恶性肿瘤中占首要地位 ......
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