高尿酸血症与心血管事件的相关性研究(1)
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[摘要] 目的 研究高尿酸血症与心血管事件发生的相关性。 方法 对2011年3～12月份在我院进行健康体检的人群进行健康调查，并按照尿酸指标进行分组，研究两组之间心血管事件的发生情况。 结果 尿酸正常组与高尿酸各组之间的心血管事件的发生情况存在明显差异(P < 0.05)；1组与2组、3组比较，心血管事件的发生率差异有统计学意义(P < 0.05)；2组与3组比较，心血管事件的发生率差异有统计学意义(P < 0.05)；尿酸升高与血糖升高、血脂升高、心血管事件发生率升高具有明显相关性(P < 0.05)。 结论 高尿酸与心血管事件的发生有明显的相关性，加强对尿酸水平的控制有利于预防心血管事件的发生。
[关键词] 高尿酸血症；心血管事件；相关性
[中图分类号] R589；R54 [文献标识码] B [文章编号] 1673-9701(2012)30-0047-02
The study of relationship between hyperuricemia and cardiovascular event
KANG Zifang
Department of Internal Medicine， Zhangcha Hospital of Foshan City in Guangdong Province， Foshan 528000， China
[Abstract] Objective To investigate the relationship between hyperuricemia and cardiovascular event. Methods The body examination data was collected from March to December， 2011. The groups were divided by the hyperuricemia levels and the rate of cardiovascular event was studied. Results The rates in normal group and hyperuricemia groups were significantly different (P < 0.05)； The rate in group one was significantly different compared with the group two and three (P < 0.05)； The rate in group two was significantly different compared with the group three (P < 0.05)； The serum uric acid was positive related with lipids and the rate of cardiovascular event (P < 0.05). Conclusion The hyperuricemia is related significantly with cardiovascular event， and it is beneficent to prevent the cardiovascular event by controlling the hyperuricemia.
[Key words] Hyperuricemia； Cardiovascular event； Relationship
高尿酸血症与心血管事件的关系受到国内外心血管研究机构的关注[1]，有流行病学研究结果表明高尿酸血症与冠心病等心血管疾病的发生具有明显的相关性[2，3]，更有国外研究表明高尿酸是高血压的独立危险因素，进一步证明了高尿酸指标对心血管疾病预测的重要性。但也有研究结论提出了相反的意见 ......
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