生长抑素对单纯性肠梗阻的辅助治疗效果观察(1)
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[摘要] 目的 观察生长抑素治疗单纯性肠梗阻的临床疗效。 方法 将到本院就治的52例单纯性肠梗阻患者随机分为两组，对照组22例给予常规治疗，治疗组30例在常规治疗基础上给予生长抑素治疗，观察两组治疗效果。 结果 治疗组、对照组治疗总有效率分别为100.00%、72.27%，治疗组治疗效果明显高于对照组(P < 0.05)；治疗组治疗后24 h血浆内毒素、D-乳酸含量均少于对照组(P < 0.05)；治疗组治疗7 d后血清TNF-α、IL-6含量均低于对照组(P <0.05)。 结论 生长抑素治疗单纯性肠梗阻，能稳定肠黏膜，减少并清除内毒素吸收，提高保守治疗成功率，值得临床广泛推广。
[关键词] 单纯性肠梗阻；生长抑素；醋酸奥曲肽
[中图分类号] R574.2 [文献标识码] B [文章编号] 1673-9701(2012)30-0070-02
The effect of somatostatin in adjuvant therapy of patient with simple obstruction
HUANG Liangxi XIE Chunfa CAI Boji LIN Feihe
Department of General Surgery，Chenghai District People’s Hospital of Shantou City in Guangdong Province， Shantou 515800， China
[Abstract] Objective To observe the clinical efficacy of somatostatin treatment of simple obstruction. Methods Randomly divided 52 cases of patients with simple obstruction which come to our hospital into two groups， 22 patients in the control group received conventional therapy， 30 patients in the treatment group received conventional therapy and somatostatin treatment，observed treatment effect. Results The treatment group and the control group total effective rate for 100.00%、72.27%.The therapeutic effect of the treatment group was significantly higher than that in the control group(P < 0.05)； the 24 h plasma levels of toxins， D-lactic acid content of treatment group were less than the control group(P < 0.05)； after 7 days of treatment，serum TNF-α，、IL-6 levels of treatment group were lower than the control group (P < 0.05). Conclusion Somatostatin treatment of simple obstruction， can stabilize the intestinal mucosa， reduce and remove endotoxin absorption and improve the success rate of conservative treatment worthy of clinical widely promoted ......
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