持续泵注生长抑素治疗急性胰腺炎后发生低血糖反应的护理体会(1)
[摘要] 目的 探讨持续泵注生长抑素治疗急性胰腺炎发生低血糖反应的护理方法。 方法 对174例急性胰腺炎患者泵注生长抑素治疗后，采用单独、持续给药，密切观察血糖变化，加强饮食护理及营养支持、健康宣教等护理，总结持续泵注生长抑素治疗急性胰腺炎发生低血糖的护理体会。 结果 发生低血糖反应的17例患者经过及时治疗及系统护理，均未发生低血糖昏迷等严重并发症，病情稳定后出院。 结论 持续泵注生长抑素治疗急性胰腺炎，通过科学的用药指导、及时治疗及系统护理，可以极大程度减少患者的低血糖反应，提高急性胰腺炎的抢救成功率。
[关键词] 生长抑素；急性胰腺炎；低血糖反应；护理
[中图分类号] R473.5 [文献标识码] B [文章编号] 1673-9701(2017)10-0152-03
Nursing experience of the occurrence of hypoglycemia reaction after continuous infusion of somatostatin in the treatment of acute pancreatitis
JIN Hongfang ZHANG Zengyu TIAN Jun
Department of Gastroenterology， Hangzhou Xiaoshan District First People's Hospital， Hangzhou 311201， China
[Abstract] Objective To explore the nursing method of the occurrence of hypoglycemia reaction after continuous infusion of somatostatin in the treatment of acute pancreatitis. Methods 174 patients with acute pancreatitis were treated with separate and sustained administration after the injection of somatostatin treatment. The changes of blood glucose were observed. The cares including diet and nutritional support and health education were strengthened. Nursing experience of the occurrence of hypoglycemia reaction after continuous injection of somatostatin in the treatment of acute pancreatitis was summarized. Results 17 patients with hypoglycemia had no any serious complications such as hypoglycemia and coma after being treated in a timely and systematic manner. They were discharged from the hospital after stable condition. Conclusion Continuous injection of somatostatin in the treatment of acute pancreatitiscan reduce the patient's hypoglycemia reaction to a great extent and improve the success rate of acute pancreatitis rescue， through scientific medication guidance， timely treatment and systematic care.
[Key words] Somatostatin； Acute pancreatitis； Hypoglycemia； Nursing
急性胰腺炎(acute pancreatitis，AP)屬于一种急腹症，在临床极为常见，是一种炎症反应，发生机制为胰腺内胰酶被激活后在多种病因的作用下引发胰腺组织自身消化、出血等，严重情况下还会引发胰腺组织坏死。近年来，其发病率日益升高，严重影响着患者的身体健康，威胁着患者的生命安全。该病具有起病较急、病情较快、发展速度快、并发症较多、死亡率较高等特点，相关医学调查资料表明，急性胰腺炎达到约9%～20%的病死率。因此，积极采取有效措施预防患者病情恶化、改善预后具有重要的临床意义[1，2]。生长抑素属于一种环状十四氨基酸肽，由人工合成，在急性胰腺炎的治疗中，临床通常采用生长抑素，其能够促进胰酶分泌减少，在极大程度上保护胰腺细胞[3]，但是也可能引发低血糖反应。本研究总结持续泵注生长抑素治疗急性胰腺炎发生低血糖反应的护理体会，现报道如下。
1 资料与方法
1.1 一般资料
选择我科2015年1月1日～12月31日收治的174例急性胰腺炎患者，纳入标准：所有患者均符合《中国急性胰腺炎诊治指南》(中华医学会消化病学分会制定)标准[4]，均经B超、CT、血常规、血和尿淀粉酶等检查确诊为急性胰腺炎且无并发症发生。其中男118例，女56例；年龄21～84岁，平均52.5岁；住院天数5～17 d，均采取非手术治疗，发生低血糖反应17例，其中男13例，女4例，年龄26～45岁，9例发生在晚餐前后，3例发生在凌晨，3例发生在其他时间段，2例发生在泵注生长抑素后，血糖最低为1.5 mmol/L，最高为5.6 mmol/L。, http://www.100md.com(金红芳 章锃瑜 田军)
[关键词] 生长抑素；急性胰腺炎；低血糖反应；护理
[中图分类号] R473.5 [文献标识码] B [文章编号] 1673-9701(2017)10-0152-03
Nursing experience of the occurrence of hypoglycemia reaction after continuous infusion of somatostatin in the treatment of acute pancreatitis
JIN Hongfang ZHANG Zengyu TIAN Jun
Department of Gastroenterology， Hangzhou Xiaoshan District First People's Hospital， Hangzhou 311201， China
[Abstract] Objective To explore the nursing method of the occurrence of hypoglycemia reaction after continuous infusion of somatostatin in the treatment of acute pancreatitis. Methods 174 patients with acute pancreatitis were treated with separate and sustained administration after the injection of somatostatin treatment. The changes of blood glucose were observed. The cares including diet and nutritional support and health education were strengthened. Nursing experience of the occurrence of hypoglycemia reaction after continuous injection of somatostatin in the treatment of acute pancreatitis was summarized. Results 17 patients with hypoglycemia had no any serious complications such as hypoglycemia and coma after being treated in a timely and systematic manner. They were discharged from the hospital after stable condition. Conclusion Continuous injection of somatostatin in the treatment of acute pancreatitiscan reduce the patient's hypoglycemia reaction to a great extent and improve the success rate of acute pancreatitis rescue， through scientific medication guidance， timely treatment and systematic care.
[Key words] Somatostatin； Acute pancreatitis； Hypoglycemia； Nursing
急性胰腺炎(acute pancreatitis，AP)屬于一种急腹症，在临床极为常见，是一种炎症反应，发生机制为胰腺内胰酶被激活后在多种病因的作用下引发胰腺组织自身消化、出血等，严重情况下还会引发胰腺组织坏死。近年来，其发病率日益升高，严重影响着患者的身体健康，威胁着患者的生命安全。该病具有起病较急、病情较快、发展速度快、并发症较多、死亡率较高等特点，相关医学调查资料表明，急性胰腺炎达到约9%～20%的病死率。因此，积极采取有效措施预防患者病情恶化、改善预后具有重要的临床意义[1，2]。生长抑素属于一种环状十四氨基酸肽，由人工合成，在急性胰腺炎的治疗中，临床通常采用生长抑素，其能够促进胰酶分泌减少，在极大程度上保护胰腺细胞[3]，但是也可能引发低血糖反应。本研究总结持续泵注生长抑素治疗急性胰腺炎发生低血糖反应的护理体会，现报道如下。
1 资料与方法
1.1 一般资料
选择我科2015年1月1日～12月31日收治的174例急性胰腺炎患者，纳入标准：所有患者均符合《中国急性胰腺炎诊治指南》(中华医学会消化病学分会制定)标准[4]，均经B超、CT、血常规、血和尿淀粉酶等检查确诊为急性胰腺炎且无并发症发生。其中男118例，女56例；年龄21～84岁，平均52.5岁；住院天数5～17 d，均采取非手术治疗，发生低血糖反应17例，其中男13例，女4例，年龄26～45岁，9例发生在晚餐前后，3例发生在凌晨，3例发生在其他时间段，2例发生在泵注生长抑素后，血糖最低为1.5 mmol/L，最高为5.6 mmol/L。, http://www.100md.com(金红芳 章锃瑜 田军)