腹腔镜胃癌根治术治疗进展期胃癌的临床研究(1)
[摘要] 目的 探討腹腔镜胃癌根治术治疗进展期胃癌的手术效果，并与开腹胃癌根治术治疗进展期胃癌的临床效果进行对比分析。 方法 选取2015年1月～2017年1月在本院接受治疗的62例进展期胃癌患者作为研究对象，其中32例采取腹腔镜胃癌根治术，30例采取开腹胃癌根治术。对两组的手术时间、术中出血量、肛门排气时间、下床时间及并发症发生率进行对比分析。 结果 腹腔镜组的手术时间与对照组比较，差异不显著(P>0.05)。腹腔镜组的术中出血量显著少于对照组，差异有统计学意义(P<0.05)，术后肛门排气时间、下床时间显著短于对照组，差异有统计学意义(P<0.05)。腹腔镜组术后发生吻合口瘘1例、切口感染0例、肺部感染2例、肠梗阻1例，对照组术后发生吻合口瘘2例、切口感染3例、肺部感染1例、肠梗阻3例，两组术后并发症发生率分别为12.5%、30.0%，腹腔镜组术后并发症发生率显著低于对照组，组间比较差异有统计学意义(P<0.05)。 结论 腹腔镜胃癌根治术较开腹胃癌根治术治疗进展期胃癌更具优势，可以减少术中出血量、促进患者术后尽快恢复、术后并发症少，有利于显著改善患者的预后。
[关键词] 进展期胃癌；腹腔镜胃癌根治术；开腹胃癌根治术；并发症
[中图分类号] R735.2 [文献标识码] B [文章编号] 1673-9701(2018)04-0101-04
[Abstract] Objective To investigate the effect of laparoscopic radical gastrectomy in the treatment of advanced gastric cancer and to compare its clinical efficacy with that of open radical gastrectomy. Methods Totally 62 patients with advanced gastric cancer treated in our hospital from January 2015 to January 2017 were selected as the study subjects. Among them， 32 patients underwent radical laparoscopic radical gastrectomy and 30 underwent open radical gastrectomy. The operation time， intraoperative blood loss， anal exhaust time， the time of getting out of bed and complication rate were compared between the two groups. Results There was no significant difference in the operation time between the laparoscopic group and the control group(P>0.05). The intraoperative bleeding of the laparoscopic group was significantly less than that of the control group， and the difference was statistically significant(P<0.05). Postoperative anal exhaust time， the time of getting out of bed was significantly shorter than that of the control group， and the difference was statistically significant(P<0.05). There were 1 case of anastomotic fistula， no case of incision infection， 2 cases of pulmonary infection and 1 case of intestinal obstruction after operation in laparoscopic group. There were 2 cases of anastomotic leakage， 3 cases of incision infection， 1 case of lung infection and 3 cases of intestinal obstruction in the control group. The incidence of postoperative complications in two groups was 12.5% and 30.0% respectively. The incidence of postoperative complications in the laparoscopic group was significantly lower than that in the control group. There was significant difference between the two groups(P<0.05). Conclusion Laparoscopic radical gastrectomy is superior to open radical gastrectomy in the treatment of advanced gastric cancer. It can reduce intraoperative blood loss and promote recovery as soon as possible after operation， with less postoperative complications， and is beneficial to significantly improve the prognosis of patients., http://www.100md.com(周小帅 洪晓明 童优君)
[关键词] 进展期胃癌；腹腔镜胃癌根治术；开腹胃癌根治术；并发症
[中图分类号] R735.2 [文献标识码] B [文章编号] 1673-9701(2018)04-0101-04
[Abstract] Objective To investigate the effect of laparoscopic radical gastrectomy in the treatment of advanced gastric cancer and to compare its clinical efficacy with that of open radical gastrectomy. Methods Totally 62 patients with advanced gastric cancer treated in our hospital from January 2015 to January 2017 were selected as the study subjects. Among them， 32 patients underwent radical laparoscopic radical gastrectomy and 30 underwent open radical gastrectomy. The operation time， intraoperative blood loss， anal exhaust time， the time of getting out of bed and complication rate were compared between the two groups. Results There was no significant difference in the operation time between the laparoscopic group and the control group(P>0.05). The intraoperative bleeding of the laparoscopic group was significantly less than that of the control group， and the difference was statistically significant(P<0.05). Postoperative anal exhaust time， the time of getting out of bed was significantly shorter than that of the control group， and the difference was statistically significant(P<0.05). There were 1 case of anastomotic fistula， no case of incision infection， 2 cases of pulmonary infection and 1 case of intestinal obstruction after operation in laparoscopic group. There were 2 cases of anastomotic leakage， 3 cases of incision infection， 1 case of lung infection and 3 cases of intestinal obstruction in the control group. The incidence of postoperative complications in two groups was 12.5% and 30.0% respectively. The incidence of postoperative complications in the laparoscopic group was significantly lower than that in the control group. There was significant difference between the two groups(P<0.05). Conclusion Laparoscopic radical gastrectomy is superior to open radical gastrectomy in the treatment of advanced gastric cancer. It can reduce intraoperative blood loss and promote recovery as soon as possible after operation， with less postoperative complications， and is beneficial to significantly improve the prognosis of patients., http://www.100md.com(周小帅 洪晓明 童优君)