高危型人乳头瘤病毒感染的相关危险因素分析(1)
[摘要] 目的 探讨高危型人乳头瘤病毒(high-risk human papillomavirus，HR-HPV)感染的相关危险因素。 方法 选取2016年11月～2017年10月HR-HPV检测高危型及疑似高危型阳性者60例为感染组，HR-HPV检测阴性者60例为对照组，两组患者均填写自行设计的《HR-HPV感染相关因素调查表》，调查结果采用SPSS19.0进行统计分析。 结果 经单因素分析的χ2檢验，妊娠次数、流产次数、初次性生活年龄、性伴侣数、性生活次数、避孕方式、性交出血、阴道炎、宫颈炎和泌尿感染这10个因素差异有统计学意义(P<0.05)。将上述差异有统计学意义的10个因素作为自变量，HR-HPV感染作为因变量进行二分类Logistic回归分析发现，初次性生活年龄、性伴侣数、避孕方式、性交出血、宫颈炎这5个因素是HR-HPV感染的危险因素(OR>1)。 结论 HR-HPV感染与多种因素相关，初次性生活年龄过早、多个性伴侣、无保护的避孕方式、性交出血和宫颈炎是HR-HPV感染的高危因素。应加强对此类患者的健康宣教，从而减少HR-HPV感染的发生。
[关键词] 高危型人乳头瘤病毒；感染；危险因素；宫颈癌；宫颈上皮内瘤变
[中图分类号] R711.3 [文献标识码] B [文章编号] 1673-9701(2018)19-0057-04
Analysis on the relevant risk factors for High risk human papillomavirus infection
ZHANG Weiling ZHAO Shanqiong
Department of Gynecology， Ningbo Hospital of TCM， Ningbo 315010， China
[Abstract] Objective To investigate the relevant risk factors of high-risk human papillomavirus (HR-HPV) infection. Methods From November 2016 to October 2017， 60 cases of high-risk type and suspected high-risk type of positive HR-HPV test were selected as the infection group. 60 cases of negative HR-HPV test were selected as the control group. Both groups of patients filled in self-designed "survey of HR-HPV infection-related factors". The results were statistically analyzed by SPSS19.0. Results According to the univariateχ2 test， the differences of the 10 factors of the number of pregnancies， the number of abortions， the age of first-time sex life， number of sex partners， number of sexual intercourses， contraceptive methods， sexual intercourse bleeding， vaginitis， cervicitis and urinary tract infection were statistically significant(P<0.05).The above-mentioned 10 factors with statistically significant differences were taken as independent variables， and HR-HPV infection was taken as a dependent variable， dichotomous Logistic regression analysis was carried out， finding that the five factors of the age of first -time sex life， number of sex partners， contraceptive methods， sexual intercourse bleeding and cervicitis were the risk factors of HR-HPV infection (OR>1). Conclusion HR-HPV infection is associated with many factors. Young age of first-time sexual life， multiple sexual partners， unprotected forms of contraception， sexual bleeding and cervicitis are the high risk factors for HR-HPV infection. Health education should be strengthened for such patients， thus reducing the incidence of HR-HPV infection.
[Key words] High-risk human papillomavirus(HR-HPV)； Infection； Risk factors； Cervical cancer； Cervical intraepithelial neoplasia, 百拇医药(张蔚苓 赵珊琼)
[关键词] 高危型人乳头瘤病毒；感染；危险因素；宫颈癌；宫颈上皮内瘤变
[中图分类号] R711.3 [文献标识码] B [文章编号] 1673-9701(2018)19-0057-04
Analysis on the relevant risk factors for High risk human papillomavirus infection
ZHANG Weiling ZHAO Shanqiong
Department of Gynecology， Ningbo Hospital of TCM， Ningbo 315010， China
[Abstract] Objective To investigate the relevant risk factors of high-risk human papillomavirus (HR-HPV) infection. Methods From November 2016 to October 2017， 60 cases of high-risk type and suspected high-risk type of positive HR-HPV test were selected as the infection group. 60 cases of negative HR-HPV test were selected as the control group. Both groups of patients filled in self-designed "survey of HR-HPV infection-related factors". The results were statistically analyzed by SPSS19.0. Results According to the univariateχ2 test， the differences of the 10 factors of the number of pregnancies， the number of abortions， the age of first-time sex life， number of sex partners， number of sexual intercourses， contraceptive methods， sexual intercourse bleeding， vaginitis， cervicitis and urinary tract infection were statistically significant(P<0.05).The above-mentioned 10 factors with statistically significant differences were taken as independent variables， and HR-HPV infection was taken as a dependent variable， dichotomous Logistic regression analysis was carried out， finding that the five factors of the age of first -time sex life， number of sex partners， contraceptive methods， sexual intercourse bleeding and cervicitis were the risk factors of HR-HPV infection (OR>1). Conclusion HR-HPV infection is associated with many factors. Young age of first-time sexual life， multiple sexual partners， unprotected forms of contraception， sexual bleeding and cervicitis are the high risk factors for HR-HPV infection. Health education should be strengthened for such patients， thus reducing the incidence of HR-HPV infection.
[Key words] High-risk human papillomavirus(HR-HPV)； Infection； Risk factors； Cervical cancer； Cervical intraepithelial neoplasia, 百拇医药(张蔚苓 赵珊琼)