[摘要] 目的 考察餐前空腹血糖联合糖化血红蛋白在妊娠糖尿病筛查中的效果。 方法 选取2017年3月～2018年9月在我院治疗的妊娠糖尿病患者220例作为研究组，另外选取同期的正常妊娠孕妇100例作为对照组，比较兩组患者的临床基线数据，测定糖化血红蛋白(HbA1c)、空腹血糖(FPG)及75 g口服葡萄糖耐量实验(OGTT)1 h、2 h的水平，并采用受试者工作特征曲线(ROC)分析HbA1c联合FPG对妊娠糖尿病的诊断效果。 结果 研究组患者的FPG、75 g葡萄糖耐量1 h、2 h及HbA1c水平均显著高于对照组，差异有统计学意义(P<0.05);研究组患者的FPG和HbA1c的阳性率均显著高于对照组，差异有统计学意义(P<0.05);FPG及HbA1c联合应用诊断妊娠糖尿病的特异性、灵敏度及准确性均较高。 结论 餐前空腹血糖联合HbA1c对妊娠糖尿病诊断的灵敏度和准确性较高，临床可推荐应用。

    [关键词] 空腹血糖;糖化血红蛋白;妊娠糖尿病;口服葡萄糖耐量实验

    [中图分类号] R714.25 [文献标识码] B [文章编号] 1673-9701(2019)22-0054-03

    [Abstract] Objective To investigate the effect of pre-meal fasting blood glucose combined with glycosylated hemoglobin in screening for gestational diabetes. Methods A total of 220 patients with gestational diabetes mellitus who were treated in our hospital from March 2017 to September 2018 were enrolled as the study group. Another 100 normal pregnant women were selected as the control group. The clinical baseline data of the two groups were compared. The glycosylated hemoglobin ......