活血化瘀类中药治疗子宫内膜异位症作用 机制的研究进展
孟繁词 张天婵 于洋 韩莹 丛慧芳〔摘要〕 子宫内膜异位症是一种激素依赖性疾病,已成为妇科及生殖医学科的难题,长期困扰女性,严重影响了育龄期妇女的生活质量。中医学认为血瘀是本病的基本病机,在治疗上当着重选择活血化瘀类中药。综合2016年至2021年国内外相关文献资料,从下调炎症因子的相对表达、诱导异位内膜细胞凋亡、抑制血管生成、调节肠道菌群、免疫调节等方面阐明活血化瘀类中药治疗子宫内膜异位症的作用途径及靶点,使其作用机制得到更全面的揭示。
〔关键词〕 子宫内膜异位症;血瘀;中药;活血化瘀;作用机制
〔中图分类号〕R271.19? ? ? ?〔文献标志码〕A? ? ? ?〔文章编号〕doi:10.3969/j.issn.1674-070X.2021.08.030
Research Progress on Mechanism of Endometriosis Treated by Traditional Chinese
Medicine of Promoting Blood Circulation and Removing Blood Stasis
MENG Fanci1, ZHANG Tianchan2, YU Yang2, HAN Ying1, CONG Huifang2*
(1. Heilongjiang University of Chinese Medicine, Harbin, Heilongjiang 150040, China; 2. The Second Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, Heilongjiang 150001, China)
〔Abstract〕 Endometriosis is a hormone dependent disease, which has become a difficult problem in gynecology and reproductive medicine. It has long plagued women and seriously affected the quality of life of women of childbearing age. Traditional Chinese medicine believes that blood stasis is the basic pathogenesis of the disease ......
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