坎地沙坦酯加呋塞米联合治疗原发性高血压患者的疗效探讨(2)
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综上,该研究提示坎地沙坦酯加呋塞米联合治疗原发性高血压是安全、有效、稳定的。
[参考文献]
[1] 王文.2009年《中国高血压防治指南》(基层版)适用于广大基层医生[J].中国医学前沿,2010,2(1):57-59.
[2] 周继勤.坎地沙坦酯治疗老年人轻中度高血压对左室舒张功能的影响[J].当代医学,2009,15(6):161.
[3] Somasundaram,Arumugram,Rajarajan A, et al. Thandavarayan;Candesartan cilexetil protects from cardiac myosin induced cardiotoxicity via reduction of endoplasmic reticulum stress and apoptosis in rats:Involvement of ACE2-Ang(1-7)-mas axis[J].Toxicology,2012,291:139-145.
[4] Shinsuke Nakamura,Kazuhiro Tsuruma.Candesartan,an angiotensin II type 1 receptor antagonist,inhibits pathological retinal neovascularization by downregulating VEGF receptor-2 expression[J].European Journal of Pharmacology,2012,685:8-14.
[5] Hae-Young Lee,Bum-Kee Hong,Wook Jin Chung,et al.Phase IV,8-Week,Multicenter,Randomized,Active Treatment-Controlled,Parallel Group,Efficacy,and Tolerability study of High-Dose Candesartan Cilexetil Combined With Hydrochlorothiazide in Korean Adults With Stage II Hypertension[J].Clinical Therapeutics,2011(33):1043-1056.
(收稿日期:2013-07-03)
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