重症监护病房与普通病房铜绿假单胞菌耐药性比较及治疗效果差异(1)
[摘要] 目的 通过对比重症监护病房(ICU)与普通病房(GW)铜绿假单胞菌(PA)的细菌耐药性情况，为临床合理用药提供依据。方法 用微量肉汤稀释法检测2010年8月—2014年8月分离出PA的最低抑菌浓度(MIC)并观察PA的细菌的形态及不同给药方案的治疗效果。 结果 ICU分离出PA的MIC范围明显高于GW，两类病房PA的细菌形态无显著差异，ICU与GW治疗有效率分别为91.03%、92.70%。结论 PA在ICU耐药性明显高于GW，头孢他啶可作为GW 患者PA感染的首选，对于ICU患者需联合用药。
[关键词] 铜绿假单胞菌；耐药性；ICU；普通病房；最低抑菌浓度；治疗效果
[中图分类号] R978.1 [文献标识码] A [文章编号] 1674-0742(2015)11(b)-0053-03
[Abstract] Objective To provide a basis for clinical rational use of drugs by comparing the drug resistance of Pseudomonas aeruginosa (PA) in intensive care unit (ICU) with that in general ward (GW). Methods The minimal inhibitory concentration (MIC) of PA was isolated from August 2010 to August 2014 by using broth dilution method. And the morphology of the bacteria and the effect of different treatment regimen for PA were observed. Results The MIC range of ICU was significantly wider than that of GW. And there was no significant difference between the two types of PA. The response rate was 91.03% and 92.70% respectively in ICU and GW. Conclusion The drug resistance of PA in ICU was significantly higher than that in GW. And ceftazidime was the first choice for PA infection in GW patients ......
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[关键词] 铜绿假单胞菌；耐药性；ICU；普通病房；最低抑菌浓度；治疗效果
[中图分类号] R978.1 [文献标识码] A [文章编号] 1674-0742(2015)11(b)-0053-03
[Abstract] Objective To provide a basis for clinical rational use of drugs by comparing the drug resistance of Pseudomonas aeruginosa (PA) in intensive care unit (ICU) with that in general ward (GW). Methods The minimal inhibitory concentration (MIC) of PA was isolated from August 2010 to August 2014 by using broth dilution method. And the morphology of the bacteria and the effect of different treatment regimen for PA were observed. Results The MIC range of ICU was significantly wider than that of GW. And there was no significant difference between the two types of PA. The response rate was 91.03% and 92.70% respectively in ICU and GW. Conclusion The drug resistance of PA in ICU was significantly higher than that in GW. And ceftazidime was the first choice for PA infection in GW patients ......
您现在查看是摘要页，全文长 3336 字符。