绝经后女性乳腺增生运用芳香化酶抑制剂治疗的分析(1)
[摘要] 目的 探讨应用芳香化酶抑制剂治疗绝经后乳腺增生的临床应用效果，分析其临床应用价值。方法 整群选取2014年3月—2016年3月期间在该院接诊的142例女性绝经后乳腺增生患者，根据临床治疗方法不同，将其分为观察组(n=71，采用芳香化酶抑制剂治疗)和对照组(n=71，采用他莫昔芬治疗)，服药后3个月给予患者复查，了解患者的增生临床症状，观察患者的不良反应，对组间临床疗效进行对比，对其数据进行统计学处理。结果 在接受不同治疗情况下，观察组患者左侧乳腺导管为(0.06±0.02)，对照组为(0.13±0.07)，观察组患者右侧乳腺导管为(0.07±0.03)，对照组为(0.14±0.06)，观察组患者乳腺纹理增粗左侧发生率为94.36%，右侧为95.77%，对照组患者乳腺纹理增粗左侧发生率为52.11%，右侧为54.92%，比较差异有统计学意义(P<0.05)；观察组患者上呼吸道感染发生率为2.81%，盗汗发生率为1.41%，疼痛发生率为2.81%，对照组分别为18.31%，12.67%，21.12%，對比差异有统计学意义(P<0.05)。结论 在当前女性绝经乳腺增生患者临床治疗过程中，采用芳香化酶抑制剂治疗属于理想的治疗方法，有效改善患者增生症状，安全性高，不良反应少，值得临床推广和应用。
[关键词] 绝经；女性；乳腺增生；芳香化酶抑制剂；疗效；观察
[中图分类号] R5 [文献标识码] A [文章编号] 1674-0742(2017)01(c)-0001-03
Analysis of Application of Arimedex Treatment for Post-menopause Female Mammary Gland
YUE Yan-hong， ZENG Yan， ZHENG Hua-fang
Department of Breast， Meishan City of Traditional Chinese Hospital， Meishan， Sichuan Province， 620010 China
[Abstract] Objective To discuss the clinical application effect of arimedex treatment for post-menopause female mammary gland and analyze the clinical application value. Methods 142 cases of female patients with post-menopause mammary gland treated in our hospital from March 2014 to March 2016 were group selected and divided into two groups with 71 cases in each according to different clinical treatment methods， the observation， the observation group were treated with arimedex， while the control group were treated with tamoxifen， and the patients were reviewed in 3 months after medication， and the clinical symptom of hyperplasia of patients were known， and the adverse reactions of patients were observed and the clinical curative effect of patients was compared， and the data were statistically processed. Results After treatment， the left and right mammary gland duct was (0.06±0.02) and (0.07±0.03)in the observation group and (0.13±0.07) and (0.14±0.06) in the control group， and the difference in the left and right breast texture thickening in the observation group had statistical significance(94.36%， 95.77%)， and the difference in the left and right breast texture thickening in the control group had statistical significance(52.11%， 54.92%)， and the difference had statistical significance (P<0.05)， and the differences in the incidence rates of upper respiratory tract infection， night sweat and pains between the observation group and the control group had statistical significance by comparison，(2.81%，1.41%，2.81% vs 18.31%，12.67%，21.12%)，the difference was statistically significant(P<0.05). Conclusion In the clinical treatment course， the arimedex treatment is an ideal method， which can effectively improve the hyperplasia symptoms of patients with high safety and few adverse reactions， which is worth clinical promotion and application., 百拇医药(岳雁鸿 曾燕 郑华芳)
[关键词] 绝经；女性；乳腺增生；芳香化酶抑制剂；疗效；观察
[中图分类号] R5 [文献标识码] A [文章编号] 1674-0742(2017)01(c)-0001-03
Analysis of Application of Arimedex Treatment for Post-menopause Female Mammary Gland
YUE Yan-hong， ZENG Yan， ZHENG Hua-fang
Department of Breast， Meishan City of Traditional Chinese Hospital， Meishan， Sichuan Province， 620010 China
[Abstract] Objective To discuss the clinical application effect of arimedex treatment for post-menopause female mammary gland and analyze the clinical application value. Methods 142 cases of female patients with post-menopause mammary gland treated in our hospital from March 2014 to March 2016 were group selected and divided into two groups with 71 cases in each according to different clinical treatment methods， the observation， the observation group were treated with arimedex， while the control group were treated with tamoxifen， and the patients were reviewed in 3 months after medication， and the clinical symptom of hyperplasia of patients were known， and the adverse reactions of patients were observed and the clinical curative effect of patients was compared， and the data were statistically processed. Results After treatment， the left and right mammary gland duct was (0.06±0.02) and (0.07±0.03)in the observation group and (0.13±0.07) and (0.14±0.06) in the control group， and the difference in the left and right breast texture thickening in the observation group had statistical significance(94.36%， 95.77%)， and the difference in the left and right breast texture thickening in the control group had statistical significance(52.11%， 54.92%)， and the difference had statistical significance (P<0.05)， and the differences in the incidence rates of upper respiratory tract infection， night sweat and pains between the observation group and the control group had statistical significance by comparison，(2.81%，1.41%，2.81% vs 18.31%，12.67%，21.12%)，the difference was statistically significant(P<0.05). Conclusion In the clinical treatment course， the arimedex treatment is an ideal method， which can effectively improve the hyperplasia symptoms of patients with high safety and few adverse reactions， which is worth clinical promotion and application., 百拇医药(岳雁鸿 曾燕 郑华芳)