尿微量白蛋白与肌酐比值及24 h尿蛋白在妊娠期高血压诊断中的价值(1)
[摘要] 目的 探讨尿微量白蛋白与肌酐比值(UACR)与24 h尿蛋白定量(UTP)在妊娠期高血压疾病诊断中的应用价值。方法 依据国际分类标准将方便选取2017年3—11月该院收治的216例妊娠期高血压疾病患者分为妊娠期高血压组(87例)、子痫前期组(55例)、子痫组(43例)和慢性高血压组(31例)，另择取同期该院50名健康孕妇为对照组，测定并观察各组UACR、UTP值，线性分析UACR、UTP与妊娠期高血压病情严重程度的相关性。结果 Pearson线性分析显示，妊娠期高血压疾病严重程度与UACR呈正相关(r=0.914，P<0.05)，与UTP呈正相关(r=0.885，P<0.05)，UACR与UTP间也呈正相关(r=0.893，P<0.05)。结论 尿微量白蛋白与肌酐比值和24 h尿蛋白定量是诊断妊娠期高血压发生和判断妊娠期高血压病情严重程度的有效指标，对妊娠期高血压疾病的预测及评估具有较高的价值，值得推广使用。
[关键词] 妊娠期高血压；尿微量白蛋白与肌酐比值；24 h尿蛋白定量
[中图分类号] R587 [文献标识码] A [文章编号] 1674-0742(2018)03(b)-0028-03
Value of Ratio of Urine Microalbumin and Creatinine and 24-hour Urine Protein in Diagnosis of Gestational Hypertension
YI Li-hua， XIA Chun-feng
Department of Obstetrics， Gaochun People’s Hospital， Nanjing， Jiangsu Province， 211300 China
[Abstract] Objective To study the application value of urine microalbumin and creatinine and 24 hour urine protein in diagnosis of gestational hypertension. Methods 216 cases of patients with gestational hypertension admitted and treated in our hospital from March to November 2017 were convenient selected and divided into four groups， including the gestational hypertension group with 87 cases， preeclampsia group with 55 cases， eclampsia group with 43 cases and chronic hypertension group with 31 cases， and 50 cases of healthy pregnant women in our hospital at the same period were selected as the control group， and the UACR，UTP values of each group were measured and observed， and the correlation between the UACR，UTP and severity of diseases of gestational hypertension was for liner analysis. Results The Pearson liner analysis showed that the severity of gestational hypertension was positively correlated with the UACA (r=0.914， P<0.05)， positively correlated with the UTP， (r=0.885， P<0.05)， also positively correlated with the UACR and UTP(r=0.893， P<0.05). Conclusion The ratio of urine microalbumin and creatinine and 24 hour urine protein are the effective indicators of diagnosis of the occurrence of gestational hypertension and determining the severity of gestational hypertension， which is of higher value to the predication and evaluation of gestational hypertension， and it is worth promotion and application.
[Key words] Gestational hypertension； Ratio of urine microalbumin and creatinine； 24 hour urine protein quantitative
妊娠期高血壓疾病是女性妊娠期特有疾病，约占全部妊娠的6%～12%[1]，以高血压、水肿、尿蛋白为主要临床表现，重者可引起抽搐、昏迷、脏器功能衰竭等症，甚至危及生命，是仅次于产后出血的造成孕产妇死亡的第2位原因[2]。该病可累及全身多系统器官，其中以肾损害最为常见，因此，早期确诊妊娠期高血压病予并于可逆期积极进行治疗干预对改善患者预后至关重要[3]。该院近年来以UACR和UTP诊断妊娠期高血压取得理想效果，文章现以2017年3—11月该院214例妊娠期高血压疾病患者为例，对UACR和UTP诊断妊娠期高血压疾病的临床效果进行分析和探讨，现报道如下。, 百拇医药(易丽华 夏春凤)
[关键词] 妊娠期高血压；尿微量白蛋白与肌酐比值；24 h尿蛋白定量
[中图分类号] R587 [文献标识码] A [文章编号] 1674-0742(2018)03(b)-0028-03
Value of Ratio of Urine Microalbumin and Creatinine and 24-hour Urine Protein in Diagnosis of Gestational Hypertension
YI Li-hua， XIA Chun-feng
Department of Obstetrics， Gaochun People’s Hospital， Nanjing， Jiangsu Province， 211300 China
[Abstract] Objective To study the application value of urine microalbumin and creatinine and 24 hour urine protein in diagnosis of gestational hypertension. Methods 216 cases of patients with gestational hypertension admitted and treated in our hospital from March to November 2017 were convenient selected and divided into four groups， including the gestational hypertension group with 87 cases， preeclampsia group with 55 cases， eclampsia group with 43 cases and chronic hypertension group with 31 cases， and 50 cases of healthy pregnant women in our hospital at the same period were selected as the control group， and the UACR，UTP values of each group were measured and observed， and the correlation between the UACR，UTP and severity of diseases of gestational hypertension was for liner analysis. Results The Pearson liner analysis showed that the severity of gestational hypertension was positively correlated with the UACA (r=0.914， P<0.05)， positively correlated with the UTP， (r=0.885， P<0.05)， also positively correlated with the UACR and UTP(r=0.893， P<0.05). Conclusion The ratio of urine microalbumin and creatinine and 24 hour urine protein are the effective indicators of diagnosis of the occurrence of gestational hypertension and determining the severity of gestational hypertension， which is of higher value to the predication and evaluation of gestational hypertension， and it is worth promotion and application.
[Key words] Gestational hypertension； Ratio of urine microalbumin and creatinine； 24 hour urine protein quantitative
妊娠期高血壓疾病是女性妊娠期特有疾病，约占全部妊娠的6%～12%[1]，以高血压、水肿、尿蛋白为主要临床表现，重者可引起抽搐、昏迷、脏器功能衰竭等症，甚至危及生命，是仅次于产后出血的造成孕产妇死亡的第2位原因[2]。该病可累及全身多系统器官，其中以肾损害最为常见，因此，早期确诊妊娠期高血压病予并于可逆期积极进行治疗干预对改善患者预后至关重要[3]。该院近年来以UACR和UTP诊断妊娠期高血压取得理想效果，文章现以2017年3—11月该院214例妊娠期高血压疾病患者为例，对UACR和UTP诊断妊娠期高血压疾病的临床效果进行分析和探讨，现报道如下。, 百拇医药(易丽华 夏春凤)