降钙素原与C—反应蛋白联合检测对细菌感染患者的应用效果(1)
[摘要] 目的 探讨降钙素原与C-反应蛋白联合检测对细菌感染患者的应用效果。方法 该次研究方便选取该院2016年10月—2017年11月收治的55例细菌感染患者为研究组，选取同时期的55例未感染患者为对照组，分别抽取两组患者的外周静脉血进行检测，对此分析两组患者的检测结果。结果 研究组患者血清中降钙素原与C-反应蛋白的阳性检测率分别为92.73%、83.64%；血清中降钙素原与C-反应蛋白浓度分别为(6.67±1.45)ng/mL、(44.20±7.25)mg/L，均高于对照组的相关检测结果，对比差异有统计学意义(χ2=32.50、29.35，t=10.26、28.73，P<0.05)；研究組患者在治疗后，血清中降钙素原与C-反应蛋白浓度较治疗前呈显著下降趋势，治疗前后对比差异有统计学意义(P<0.05)。 结论 降钙素原与C-反应蛋白联合检测对细菌感染患者的应用效果显著，值得临床继续应用推广。
[关键词] 降钙素原；C-反应蛋白；联合检测；细菌感染
[中图分类号] R515 [文献标识码] A [文章编号] 1674-0742(2018)06(b)-0068-03
Application Effect of Procalcitonin Combined with C-reactive Protein in Testing Patients with Bacterial Infection
WANG Ping-ping
Zhengzhou Sixth People’s Hospital， Zhengzhou， Henan Province， 450015 China
[Abstract] Objective To study the application effect of procalcitonin combined with C-reactive protein in testing patients with bacterial infection. Methods 55 cases of patients with bacterial infection admitted and treated in our hospital from October 2016 to November 2017 were convenient selected as the research group， while 55 cases of patients with non-infection at the same period were selected as the control group， and the peripheral venous blood of the two groups was extracted for test， and the test results of the two groups were analyzed. Results The positive test rates and concentrations of procalcitonin combined with C-reactive protein in the research group were 92.73%， 83.64% and (6.67±1.45)ng/mL，(44.20±7.25)mg/L， which were higher than those in the control group， and the differences were statistically significant(χ2=32.50， 29.35， t=10.26， 28.73， P<0.05) ， after treatment， the serum procalcitonin combined with C-reactive protein in the research group showed a decreasing trend compared with that before treatment， and the difference before and after treatment was statistically significant(P<0.05). Conclusion The application effect of procalcitonin combined with C-reactive protein in testing patients with bacterial infection is obvious， which is worth application and promotion in clinic.
[Key words] Procalcitonin； C-reactive protein； Combined test； Bacterial infection
细菌感染性疾病属于临床上较为常见的疾病，患者患病期间会出现发热、关节疼痛、寒战等不同症状，严重者可导致感染性休克、败血症等，严重威胁患者的生命健康[1]。因此准确的早期诊断对该疾病的治疗及预后有着十分重要的作用。相关研究显示[2-3]，降钙素原与C-反应蛋白联合检测可以作为感染性疾病检测的重要标准。因此该次研究为了探讨降钙素原与C-反应蛋白联合检测对细菌感染患者的应用效果，方便选取该院2016年10月—2017年11月收治的55例细菌感染患者为研究对象，与未感染患者进行对比分析，旨在提高细菌感染患者的检测准确率，现报道如下。
1 资料与方法
1.1 一般资料
方便选取该院收治的55例细菌感染患者为研究组，以及同时期的55例未感染患者为对照组，研究组患者中男30例，女25例，年龄(42.35±5.21)岁，其中感染性休克12例、严重尿路感染11例、重症肺炎32例；对照组患者中男29例，女26例，年龄(43.58±5.19)岁。两组患者年龄、性别差异无统计学意义(P>0.05)。两组患者及家属均知情同意该次研究，且该次研究亦经过该院伦理委员会的同意。, http://www.100md.com(王平平)
[关键词] 降钙素原；C-反应蛋白；联合检测；细菌感染
[中图分类号] R515 [文献标识码] A [文章编号] 1674-0742(2018)06(b)-0068-03
Application Effect of Procalcitonin Combined with C-reactive Protein in Testing Patients with Bacterial Infection
WANG Ping-ping
Zhengzhou Sixth People’s Hospital， Zhengzhou， Henan Province， 450015 China
[Abstract] Objective To study the application effect of procalcitonin combined with C-reactive protein in testing patients with bacterial infection. Methods 55 cases of patients with bacterial infection admitted and treated in our hospital from October 2016 to November 2017 were convenient selected as the research group， while 55 cases of patients with non-infection at the same period were selected as the control group， and the peripheral venous blood of the two groups was extracted for test， and the test results of the two groups were analyzed. Results The positive test rates and concentrations of procalcitonin combined with C-reactive protein in the research group were 92.73%， 83.64% and (6.67±1.45)ng/mL，(44.20±7.25)mg/L， which were higher than those in the control group， and the differences were statistically significant(χ2=32.50， 29.35， t=10.26， 28.73， P<0.05) ， after treatment， the serum procalcitonin combined with C-reactive protein in the research group showed a decreasing trend compared with that before treatment， and the difference before and after treatment was statistically significant(P<0.05). Conclusion The application effect of procalcitonin combined with C-reactive protein in testing patients with bacterial infection is obvious， which is worth application and promotion in clinic.
[Key words] Procalcitonin； C-reactive protein； Combined test； Bacterial infection
细菌感染性疾病属于临床上较为常见的疾病，患者患病期间会出现发热、关节疼痛、寒战等不同症状，严重者可导致感染性休克、败血症等，严重威胁患者的生命健康[1]。因此准确的早期诊断对该疾病的治疗及预后有着十分重要的作用。相关研究显示[2-3]，降钙素原与C-反应蛋白联合检测可以作为感染性疾病检测的重要标准。因此该次研究为了探讨降钙素原与C-反应蛋白联合检测对细菌感染患者的应用效果，方便选取该院2016年10月—2017年11月收治的55例细菌感染患者为研究对象，与未感染患者进行对比分析，旨在提高细菌感染患者的检测准确率，现报道如下。
1 资料与方法
1.1 一般资料
方便选取该院收治的55例细菌感染患者为研究组，以及同时期的55例未感染患者为对照组，研究组患者中男30例，女25例，年龄(42.35±5.21)岁，其中感染性休克12例、严重尿路感染11例、重症肺炎32例；对照组患者中男29例，女26例，年龄(43.58±5.19)岁。两组患者年龄、性别差异无统计学意义(P>0.05)。两组患者及家属均知情同意该次研究，且该次研究亦经过该院伦理委员会的同意。, http://www.100md.com(王平平)