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诺和灵30R联合二甲双胍治疗2型糖尿病效果分析(1)
http://www.100md.com 2018年9月15日 《中外医疗》 2018年第26期
     [摘要] 目的 分析诺和灵30R联合二甲双胍治疗2型糖尿病的临床效果。 方法 随机选取2014年1月—2018年5月期间该院2型糖尿病患者100例,实施信封随机分组模式,分为观察组和对照组,各50例。分别给予诺和灵30R、诺和灵30R联合二甲双胍治疗,对比2组临床相关指标情况、不良反应发生情况、血糖达标时间。 结果 ①观察组FBG为(7.74±0.88)mmol/L、2 hPG为(8.20±1.77)mmol/L、HbAlc为(8.77±1.11)%,数据与对照组数据之间进行比较,差异有统计学意义(t=6.155 8,P=0.000 1;t=7.441 8,P=0.000 1;t=9.474 7,P=0.000 1);②观察组不良反应发生例数为1例,对照组发生例数为8例,数据之间进行比较,差异有统计学意义(χ2=5.982 9,P=0.014 4);③观察组血糖达标时间为(9.87±1.11)d;对照组血糖达标时间为(14.42±2.11)d;2組数据之间进行比较,差异有统计学意义(t=13.494 7,P=0.000 1)。 结论 诺和灵30R联合二甲双胍治疗2型糖尿病疗效较为确切,可推广。

    [关键词] 诺和灵30R;二甲双胍;2型糖尿病;效果;观察;分析

    [中图分类号] R587.1 [文献标识码] A [文章编号] 1674-0742(2018)09(b)-0105-03

    [Abstract] Objective To analyze the clinical effect of Nuoheling 30R combined with metformin in the treatment of type 2 diabetes mellitus. Methods 100 patients with type 2 diabetes mellitus in the hospital from January 2014 to May 2018 were randomly selected and enrolled with observation group of 50 case and control group, group of 50 case. The patients were treated with Nuoheling 30R and Nuoheling 30R combined with metformin. The clinical indicators of the two groups, the occurrence of adverse reactions and the time of blood glucose compliance were compared. Results 1.The FBG of the observation group was (7.74±0.88) mmol/L, the 2 hPG was (8.20±1.77) mmol/L, and the HbAlc was (8.77±1.11)%. The data were compared with the control data, and the difference was statistically significant(t=6.155 8, P=0.000 1; t=7.441 8, P=0.000 1; t=9.474 7, P=0.000 1);2.the number of adverse reactions occurred in the observation group was 1 case, and the number of cases in the control group was 8 cases. The difference was significant(χ2=5.982 9, P=0.014 4); 3.observation group blood glucose compliance time was (9.87±1.11)d; control group blood glucose compliance time was (14.42±2.11)d; two groups of data were compared, the difference was statistically significant(t=13.494 7, P=0.000 1). Conclusion Nuoheling 30R combined with metformin in the treatment of type 2 diabetes is more effective and can be promoted.

    [Key words] Nuoheling 30R; Metformin; Type 2 diabetes; Effect; Observation; Analysis

    2型糖尿病是终身性代谢性疾病,其主要是因为血糖控制不达标而产生的一种疾病,而随着社会的不断发展[1],老年人口的不断增加,患有2型糖尿病的患者呈逐年上升的趋势,严重影响我国人口质量,因此需要选择较好的方式进行治疗,从而达到一定的应用效果。该文2014年1月—2018年5月研究针对100例2型糖尿病患者,分别给予不同方法进行治疗,对比效果差异性,现报道如下。

    1 资料与方法

    1.1 一般资料

    随机选取该院收治的2型糖尿病患者100例实施信封随机分组模式。100例患者均知情了解该次研究且当面签署同意书,还获得了伦理委员会的批准。观察组男性与女性分别30例、20例,平均年龄(53.33±2.04)岁,对照组男性与女性分别31例、19例,平均年龄(53.36±2.54)岁;2组患者一般资料差异无统计学意义(P>0.05)。, 百拇医药(黄莉莉 张卫兵 魏吉林)
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