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经皮射频消融术与腹腔镜肝癌切除术治疗小肝癌的疗效(1)
http://www.100md.com 2018年12月25日 《中外医疗》 2018年第36期
     [摘要] 目的 探討经皮射频消融术与腹腔镜肝癌切除术治疗小肝癌的疗效。方法 方便选取2013年1月—2017年3月小肝癌患者70例数字表法分组为腹腔镜肝癌切除术组35例和经皮射频消融术组35例。腹腔镜肝癌切除术组进行腹腔镜肝癌切除术,经皮射频消融术组进行经皮射频消融术。比较两组疗效;手术实施的耗时、手术后患者的住院时间;手术前后患者肝癌生存质量简表评分、肝功能指标情况;手术并发症率。 结果 经皮射频消融术组疗效33例(94.29%)高于腹腔镜肝癌切除术组23例(65.71%),差异有统计学意义(χ2=10.972,P<0.05)。经皮射频消融术组手术实施的耗时、手术后患者的住院时间(45.02±10.12)min、(6.25±1.21)d优于腹腔镜肝癌切除术组(62.14±20.24)min、(8.62±2.52)d,差异有统计学意义(t=8.213、5.721,P<0.05);手术后经皮射频消融术组肝癌生存质量简表评分、肝功能指标情况优于腹腔镜肝癌切除术组,肝癌生存质量简表评分、TBIL(μmol/L)、AST(U/L)、ALT(U/L)比较,差异有统计学意义(t=5.822、7.923、8.013、8.522,P<0.05)。经皮射频消融术组手术并发症率3例(8.57%)低于腹腔镜肝癌切除术组10例(28.57%),差异有统计学意义(χ2=4.939,P<0.05)。 结论 小肝癌患者行经皮射频消融术疗效明显,可更好改善肝癌生存质量简表评分、肝功能指标情况,加速康复。

    [关键词] 经皮射频消融术;腹腔镜肝癌切除术;小肝癌;疗效

    [中图分类号] R735 [文献标识码] A [文章编号] 1674-0742(2018)12(c)-0016-03

    [Abstract] Objective To study the curative effect of percutaneous radiofrequency ablation and laparoscopic hepatectomy in treatment of small liver cancer. Methods 70 cases of patients with small liver cancer admitted and treated in our hospital from January 2013 to March 2017 were conveniently selected and randomly divided into two groups with 35 cases in each, including the laparoscopic hepatectomy group and percutaneous radiofrequency ablation group, and the curative effect, operation time, length of stay, liver cancer survival quality scale score, liver function indicators and operative complication rate before and after surgery were compared between the two groups. Results The curative effect in the percutaneous radiofrequency ablation group was higher than that in the laparoscopic hepatectomy group, [33 cases(94.29%) vs 23 cases(65.71%),(χ2=10.972,P<0.05)], and the operation time, and length of stay of patients after surgery in the percutaneous radiofrequency ablation group were better than those in the laparoscopic hepatectomy group[(45.02±10.12)min, (6.25±1.21)d vs (62.14±20.24)min, (8.62±2.52)d,the different was statistically significant(t= 8.213, 5.721, P< 0.05), after surgery, the liver cancer survival scale score and liver function indicators after surgery in the percutaneous radiofrequency ablation group were better than those in the laparoscopic hepatectomy group, and the comparison of liver cancer survival quality scale score, TBIL(μmol/L), AST(U/L), ALT(U/L) showed,the different was statistically significant(t= 5.822, 7.923, 8.013, 8.522, P< 0.05), and the operative complication rate in the percutaneous radiofrequency ablation group was lower than that in the laparoscopic hepatectomy group[3 cases(8.57%) vs 10 cases(28.57%)],the different was statistically significant(χ2=4.939,P< 0.05). Conclusion The curative effect of percutaneous radiofrequency ablation of patients with small liver cancer is more obvious, which can better improve the liver cancer survival quality scale score and liver function indicators and accelerate the recovery., 百拇医药(王艳军 黄天从 周文瑞 王高雄)
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