非小细胞肺癌患者术前增强CT与淋巴结微转移的相关性研究(1)
[摘要] 目的 探討非小细胞肺癌患者术前增强CT相关结果与术中所取淋巴结微转移之间的关系。方法 方便选取该院心胸外科2017年12月—2018年11月经根治性切除治疗的非小细胞肺癌患者50例，根据增强CT结果比较各组间淋巴结微转移的差异。 结果 肿瘤直径≥3 cm者为26例，淋巴结有微转移8例，直径<3 cm者24例，发现淋巴结微转移2例，两组间淋巴结微转移率差异有统计学意义(χ2=38.75，P<0.05)。病灶轻度强化者为21例，淋巴结有微转移3例，病灶明显强化者29例，发现淋巴结微转移7例，两组间淋巴结微转移率差异有统计学意义(χ2= 15.83，P<0.05)。淋巴结最小直径≤1.0 cm者为35例，淋巴结有微转移4例，淋巴结最小直径>1.0 cm者15例，发现淋巴结微转移6例，两组间淋巴结微转移率差异有统计学意义(χ2=45.16，P<0.05)。未发现淋巴结肿大者为33例，淋巴结有微转移5例，肺门淋巴结肿大者7例，发现淋巴结微转移1例，纵膈淋巴结肿大者5例，发现淋巴结微转移1例，肺门与纵膈淋巴结均肿大者5例，发现淋巴结微转移3例，各组间淋巴结微转移率差异有统计学意义(χ2=52.89，P<0.05)。通过组间比较发现肿瘤大小、病灶强化程度、淋巴结最小直径及淋巴结肿大位置等各组间淋巴结微转移率差异有显著性。通过多因素分析发现，肿瘤大小、淋巴结最小直径与淋巴结肿大位置与淋巴结微转移之间有相关性，但肿瘤强化程度与之关系不大。 结论 术前增强CT检查结果中肿瘤大小、淋巴结最小直径与淋巴结肿大位置与淋巴结微转移之间存在一定相关性。
[关键词] 非小细胞肺癌；术前增强CT；淋巴结微转移；相关性
[中图分类号] R5 [文献标识码] A [文章编号] 1674-0742(2019)03(b)-0016-04
[Abstract] Objective To investigate the relationship between preoperative enhanced CT findings and lymph node micrometastasis in patients with non-small cell lung cancer. Methods Convenient select a total of 50 patients with non-small cell lung cancer who underwent radical resection from December 2017 to November 2018 in our hospital were enrolled. The differences in lymph node micrometastasis between groups were compared according to the results of enhanced CT. Results There were 26 cases with tumor diameter ≥3 cm， 8 cases with lymph node metastasis， 24 cases with diameter <3 cm， and 2 cases with lymph node micrometastasis. There was significant difference in lymph node micrometastasis rate between the two groups(χ2=38.75， P<0.05). There were 21 cases with mild enhancement of lesions， 3 cases with micrometastasis in lymph nodes， 29 cases with obvious enhancement of lesions， and 7 cases with lymph node micrometastasis. There was significant difference in lymph node micrometastasis rate between the two groups(χ2=15.83， P<0.05). There were 35 cases with lymph node minimum diameter ≤1.0 cm， 4 cases with lymph node micrometastasis， 15 cases with lymph node minimum diameter>1.0 cm， and 6 cases with lymph node micrometastasis， lymph node micrometastasis rate between the two groups. The difference was significant(χ2=45.16， P<0.05). No cases of lymphadenopathy were found in 33 cases， lymph node micrometastasis in 5 cases， hilar lymph node enlargement in 7 cases， lymph node micrometastasis in 1 case， mediastinal lymph node enlargement in 5 cases， lymph node micrometastasis in 1 case， 5 cases of lung portal and mediastinal lymph nodes， and 3 cases of lymph node micrometastasis were found. There was significant difference in lymph node micrometastasis rate between groups(χ2=52.89， P<0.05). Differences in lymph node micrometastasis between the groups， such as tumor size， lesion enhancement， lymph node minimum diameter， and lymph node enlargement， were found to be significant. Multivariate analysis revealed that there was a correlation between tumor size， lymph node minimum diameter and lymph node enlargement and lymph node micrometastasis， but the degree of tumor enhancement was not related. Conclusion There is a correlation between tumor size， lymph node minimum diameter and lymph node enlargement and lymph node micrometastasis in preoperative enhanced CT findings., http://www.100md.com(丁修敬)
[关键词] 非小细胞肺癌；术前增强CT；淋巴结微转移；相关性
[中图分类号] R5 [文献标识码] A [文章编号] 1674-0742(2019)03(b)-0016-04
[Abstract] Objective To investigate the relationship between preoperative enhanced CT findings and lymph node micrometastasis in patients with non-small cell lung cancer. Methods Convenient select a total of 50 patients with non-small cell lung cancer who underwent radical resection from December 2017 to November 2018 in our hospital were enrolled. The differences in lymph node micrometastasis between groups were compared according to the results of enhanced CT. Results There were 26 cases with tumor diameter ≥3 cm， 8 cases with lymph node metastasis， 24 cases with diameter <3 cm， and 2 cases with lymph node micrometastasis. There was significant difference in lymph node micrometastasis rate between the two groups(χ2=38.75， P<0.05). There were 21 cases with mild enhancement of lesions， 3 cases with micrometastasis in lymph nodes， 29 cases with obvious enhancement of lesions， and 7 cases with lymph node micrometastasis. There was significant difference in lymph node micrometastasis rate between the two groups(χ2=15.83， P<0.05). There were 35 cases with lymph node minimum diameter ≤1.0 cm， 4 cases with lymph node micrometastasis， 15 cases with lymph node minimum diameter>1.0 cm， and 6 cases with lymph node micrometastasis， lymph node micrometastasis rate between the two groups. The difference was significant(χ2=45.16， P<0.05). No cases of lymphadenopathy were found in 33 cases， lymph node micrometastasis in 5 cases， hilar lymph node enlargement in 7 cases， lymph node micrometastasis in 1 case， mediastinal lymph node enlargement in 5 cases， lymph node micrometastasis in 1 case， 5 cases of lung portal and mediastinal lymph nodes， and 3 cases of lymph node micrometastasis were found. There was significant difference in lymph node micrometastasis rate between groups(χ2=52.89， P<0.05). Differences in lymph node micrometastasis between the groups， such as tumor size， lesion enhancement， lymph node minimum diameter， and lymph node enlargement， were found to be significant. Multivariate analysis revealed that there was a correlation between tumor size， lymph node minimum diameter and lymph node enlargement and lymph node micrometastasis， but the degree of tumor enhancement was not related. Conclusion There is a correlation between tumor size， lymph node minimum diameter and lymph node enlargement and lymph node micrometastasis in preoperative enhanced CT findings., http://www.100md.com(丁修敬)