单孔胸腔镜手术对纵隔肿瘤的临床疗效和安全性研究(1)
[摘要] 目的 探讨单孔胸腔镜手术对纵隔肿瘤的临床疗效和安全性。 方法 方便选取2016年8月—2018年7月该院收治的80例纵膈肿瘤患者，按随机数字表法分为A组(40例)和B组(40例)，A组采取三孔胸腔镜手术治疗，B组采取单孔胸腔镜手术治疗，并比较不同组患者临床疗效。结果 A组和B组患者术前患者生活质量比较以及白介素-1(IL-1)、白介素-6(IL-6)和降钙素(PCT)等疼痛应激指标比较差异无统计学意义(P>0.05)，B组患者治疗后患者生活质量比较以及IL-1、IL-6和PCT等疼痛应激指标水平明显低于A组，差异有统计学意义(P<0.05);B组患者手术时间[(92.90±17.76)min vs (129.08±38.75)min]、切口长度[(5.37±0.98)cm vs (12.93±1.69)cm]、术中出血量[(27.88±8.66)mL vs (54.20±16.00)mL]、引流时间[(3.08±0.83)d vs (5.78±0.69)d]和住院时间[(4.65±1.49)d vs (10.28±3.27)d]均明显低于A组(t=5.368、24.509、9.166、15.766、9.903，P<0.05);B组患者并發症发生率(5.00% vs 20.00%)明显低于A组，差异有统计学意义(χ2=4.114，P=0.043)。结论 单孔胸腔镜手术在纵隔肿瘤中应用效果良好，不仅能有效提高手术指标以及减缓疼痛程度，同时还能降低并发症发生率，促进患者早日康复。
, 百拇医药
[关键词] 纵膈肿瘤;三孔胸腔镜手术;单孔胸腔镜手术;临床疗效
[中图分类号] R5 [文献标识码] A [文章编号] 1674-0742(2019)08(a)-0060-04
[Abstract] Objective To investigate the clinical efficacy and safety of single-hole thoracoscopic surgery for mediastinal tumors. Methods Eighty patients with mediastinal tumor admitted to our hospital from August 2016 to July 2018 were convenient selected and randomly divided into group A (40 cases) and group B (40 cases). Group A was treated with three-hole thoracoscopic surgery. Group B was treated with single-hole thoracoscopic surgery， and the clinical efficacy of different groups of patients was compared. Results There was no significant difference in the quality of life between patients in group A and group B， and the pain stress indicators such as interleukin-1 (IL-1)， interleukin-6 (IL-6) and calcitonin (PCT) (P>0.05)， the quality of life of patients in group B and the levels of pain stress indicators such as IL-1， IL-6 and PCT were significantly lower than those in group A，the difference was statistically significant(P<0.05); the operation time in group B [(92.90±17.76)min vs (129.08±38.75)min]， length of incision [(5.37±0.98) cm vs (12.93±1.69)cm]， intraoperative blood loss [(27.88±8.66)mL vs (54.20±16.00)mL]， drainage time [(3.08±0.83) d vs (5.78±0.69) d] and hospitalization time [(4.65±1.49) d vs (10.28±3.27) d] were significantly lower than group A，the difference was statistically significant(t=5.368、 24.509、 9.166、 15.766、 9.903， P<0.05); the incidence of complications in group B (5.00% vs 20.00%) was significantly lower than that in group A，the difference was statistically significant(χ2=4.114， P=0.043). Conclusion Single-hole thoracoscopic surgery has a good effect in mediastinal tumors， which not only can effectively improve the surgical index and reduce the degree of pain， but also reduce the incidence of complications and promote the early recovery of patients., 百拇医药(马明生 王晓岩 何帆 吕向阳 刘超 董艳琼)
, 百拇医药
[关键词] 纵膈肿瘤;三孔胸腔镜手术;单孔胸腔镜手术;临床疗效
[中图分类号] R5 [文献标识码] A [文章编号] 1674-0742(2019)08(a)-0060-04
[Abstract] Objective To investigate the clinical efficacy and safety of single-hole thoracoscopic surgery for mediastinal tumors. Methods Eighty patients with mediastinal tumor admitted to our hospital from August 2016 to July 2018 were convenient selected and randomly divided into group A (40 cases) and group B (40 cases). Group A was treated with three-hole thoracoscopic surgery. Group B was treated with single-hole thoracoscopic surgery， and the clinical efficacy of different groups of patients was compared. Results There was no significant difference in the quality of life between patients in group A and group B， and the pain stress indicators such as interleukin-1 (IL-1)， interleukin-6 (IL-6) and calcitonin (PCT) (P>0.05)， the quality of life of patients in group B and the levels of pain stress indicators such as IL-1， IL-6 and PCT were significantly lower than those in group A，the difference was statistically significant(P<0.05); the operation time in group B [(92.90±17.76)min vs (129.08±38.75)min]， length of incision [(5.37±0.98) cm vs (12.93±1.69)cm]， intraoperative blood loss [(27.88±8.66)mL vs (54.20±16.00)mL]， drainage time [(3.08±0.83) d vs (5.78±0.69) d] and hospitalization time [(4.65±1.49) d vs (10.28±3.27) d] were significantly lower than group A，the difference was statistically significant(t=5.368、 24.509、 9.166、 15.766、 9.903， P<0.05); the incidence of complications in group B (5.00% vs 20.00%) was significantly lower than that in group A，the difference was statistically significant(χ2=4.114， P=0.043). Conclusion Single-hole thoracoscopic surgery has a good effect in mediastinal tumors， which not only can effectively improve the surgical index and reduce the degree of pain， but also reduce the incidence of complications and promote the early recovery of patients., 百拇医药(马明生 王晓岩 何帆 吕向阳 刘超 董艳琼)