[摘要] 随着新型免疫抑制剂的临床应用和血管吻合技术的提高,临床肝移植成功率大大提高，而严重肝脏缺血再灌注损伤所引起的移植肝功能受损始终未能解决，影响肝移植的效果。因此本文对肝脏缺血再灌注损伤的分类、机制、预防及治疗等方面予以综述。

    [关键词] 肝脏；局部缺血；再灌注损伤

    [中图分类号] R657.3[文献标识码]C [文章编号]1674-4721(2009)05(a)-020-03

    The mechanism of hepatic ischemia-reperfusion injury

    GUAN Bingxing, GU Mei

    (Beijing Tongren Hospital General Surgery,Beijing100730,China)

    [Abstract] With the new immunosuppressive agents and the clinical application of vascular anastomosis techniques improved the success rate of clinical liver transplantation greatly improved. And severe hepatic ischemia-reperfusion injury caused by impaired liver function has not yet been resolved, the effect of the impact of liver transplantation. So this article on hepatic ischemia-reperfusion injury classification, mechanism, prevention and treatment to be summarized.

    [Key words] Liver；Ischemic；Reperfusion injury

    肝移植相关的缺血再灌注损伤是指从正常体温下 ......