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妊娠期高血压综合征产妇羊水及脐血儿茶酚胺与胎儿预后的关系(1)
http://www.100md.com 2010年4月5日
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     [摘要] 目的:探讨妊娠期高血压综合征(妊高征)产妇羊水及脐血儿茶酚胺与胎儿预后的相关性,以为其预防和治疗等提供依据。方法:选取2005年3月~2009年9月于本院住院的100例妊高征产妇为研究对象,将其设为观察组,同时选取100名同期健康产妇为对照组,对两组产妇的羊水及脐血儿茶酚胺含量进行检测,并对新生儿进行检查,将结果进行总结分析。结果:经研究比较发现,观察组产妇的羊水及脐血儿茶酚胺水平明显高于对照组,且疾病越重,儿茶酚胺水平也越高,且儿茶酚胺水平越高,胎儿的宫内窘迫和发育迟缓的发生率也越高,经比较,P均<0.05,差异均有统计学意义。结论:产妇羊水与脐血儿茶酚胺水平可在一定程度上反映胎儿的情况,意义较大,应引起重视,值得进一步研究和探讨。

    [关键词] 妊娠期高血压综合征(妊高征);羊水;脐血;胎儿预后;相关性

    [中图分类号] R714.24+6 [文献标识码]A [文章编号]1674-4721(2010)04(a)-09-02

    The relationship between catecholamine of amniotic fluid of parturient with pregnancy induced hypertension and cord blood and fetal prognosis

    WEI Liyun

    (Anliu Health Centers of Wuhua County, Wuhua 514437, China)

    [Abstract] Objective: To study the relationship between catecholamine of amniotic fluid of parturient with pregnancy induced hypertension and cord blood and fetal prognosis. Methods: 100 cases parturients with pregnancy induced hypertension in our hospital from March 2005 to September 2009 were selected as observation group, and 100 cases healthy parturients were selected as control group at the same time. Then the level of catecholamine of amniotic fluid and cord blood of the two groups were tested,and the newborn were checked. And the results were summarized and analyzed. Results: According to the study, the level of catecholamine of amniotic fluid and cord blood of the observation group was higher than that of control group, and the severer the disease, the higher the level of catecholamine, and the higher the level of catecholamine, the higher the incidence of intrauterine distress and growth retardation of fetus, P<0.05, the differences had statistical significance. Conclusion: The level of catecholamine of amniotic fluid of parturient with pregnancy induced hypertension and cord blood can reflect the situation of fetus,and should be paid attention to,it is worthy of further study and discussion.

    [Key words] Pregnancy induced hypertension; Amniotic fluid; Cord blood; Fetal prognosis; Relationship

    妊娠期高血压综合征(妊高征)与胎儿的预后也有一定的关系,检测妊高征孕产妇羊水及胎儿脐血儿茶酚胺水平可从一定程度上反映胎儿的预后关系[1]。本文中笔者选取2007年3月~2009年9月于本院住院的100例妊高征产妇为研究对象,对其羊水及脐血儿茶酚胺与胎儿预后的相关性进行研究,后将结果进行总结分析,现报道如下:

    1资料与方法

    1.1一般资料

    选取2007年3月~2009年9月于本院住院的100例妊高征产妇为研究对象,将其设为观察组,同时选取100名同期健康产妇为对照组。对照组的100名健康孕产妇,年龄21~37岁,平均(29.3±2.2)岁,孕周(37+2~39+4)周。观察组的100例孕产妇,年龄22~36岁,平均(28.8±2.7)岁,孕周(37+4~39+3)周,其中,轻度妊高征25例,中度妊高征53例,重度妊高征22例。两组孕产妇在年龄、孕周等基本情况方面进行比较,P>0.05,差异无统计学意义,具有可比性。

    1.2方法

    于分娩初期将产妇的羊水进行收集,注意避免污染,剪断脐带后,收集脐血3~5 ml[2],均装于试管中,离心后于冰箱中保存,后对其中的去甲肾上腺素、肾上腺素和多巴胺水平进行统计分析,采用高效液相色谱法进行检测,后将结果进行统计比较,总结分析 ......

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